Apoptosis

Characterization of the Biochemical Pathway of Apoptosis Induced by D-glucopyranoside Derivatives from Tulbaghia violacea

Sylvester Leonard Lyantagaye · Annual Research & Review in Biology · 2013

Aim: Chinese hamster ovary (CHO) cells were used to identify the most likely apoptotic biochemical pathway induced by Methyl-α-D-glucopyranoside (MDG), D-fructofuranose-β(2→6)-methyl-α-D-glucopyranoside (DFMDG) and β-D-fructofuranosyl-(2→6)-α-D-glucopyranoside (DFDG) treatments i...

Open access Research Article 10.9734/ARRB/2014/6158

Pulmonary Arterial Hypertension and Cancer: An Update on Their Similarities

Frederic Delom & Delphine Fessart · Annual Research & Review in Biology · 2013

Pulmonary arterial hypertension (PAH) is characterized by an increase resistance of the vascular wall from pulmonary arteries leading to vascular lumen occlusion, right ventricular failure, and death. PAH has been described for many years, as a cardiovascular disease affecting th...

Open access Research Article 10.9734/ARRB/2014/5296

Fetal Myocardial Reduction in Hyperglycemic Mouse Pregnancy is Associated with Dys-regulated Expression of the Anti-apoptotic Gene Bcl-2 in the Developing Heart. Preliminary Results

J. Claudio Gutierrez, M. Renee Prater, Patricia Navarrete & Steven D. Holladay · Annual Research & Review in Biology · 2013

Aims: We previously detected significant late-gestation ventricular myocardial reduction in fetal mouse hearts from hyperglycemic dams. Flow cytometric analysis of the myocardial cells showed an enhanced rate of apoptosis, suggesting dysregulated cell death as a mechanism associa...

Open access Research Article 10.9734/ARRB/2014/5085