Role of Interstitial Angiotensin II and ATP in Mediating Renal Injury Induced by Recurrent Insulin Induced Hypoglycemia
Priyanka Prathipati, Wael Alanazi, Fakhruddin ., Debra W. Jackson & Keith E. Jackson · Annual Research & Review in Biology · 2015
Aim: The present study hypothesizes that recurrent insulin induced hypoglycemia (RIIH) elevates renal interstitial ATP levels which in turn enhances AngII production. This interrupts the normal tubuloglomerular feedback (TGF) mechanism by stimulating afferent arteriolar vasoconst...
Open access
Research Article
10.9734/ARRB/2015/16184