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Biopharmaceutics

Papers (7)

Endothelin-1 (1-31) Causes the Migration of Vascular Smooth Muscle Cells through Endothelin ETA Receptor

Yoji Kyotani, Jing Zhao, Kentaro Ozawa, Takahiko Nakagawa, Francesco Bolstad & Masanori Yoshizumi · British Journal of Pharmaceutical Research · 2016

Endothelin-1 (ET-1) is predominantly expressed in endothelial cells to modulate physiological actions, such as vasoconstriction and cell proliferation. It acts as an autocrine and paracrine factor, and has been reported to be found in increased levels in the blood of patients wit...

Open access Research Article 10.9734/bjpr/2016/29824

HPLC, Densitometric and Visible-Spectrophotometric Determination of Triclabendazole and Ivermectin

Sawsan Razeq, Asmaa El-Demerdash & Hoda El-Sanabary · British Journal of Pharmaceutical Research · 2016

Two methods were developed for simultaneous determination of triclabendazole and ivermectin, in addition to a Vis-spectrophotometric method for the analysis of ivermectin only. The first one was HPLC method in which efficient separation of two drugs was achieved on a C18 column w...

Open access Research Article 10.9734/bjpr/2016/29196

Acute and Subchronic Toxicity Studies of Aqueous, Methanolic and n-Hexane Root Extracts of Curcuma longa L. on Albino Rats

A Mohammed, A Wudil, A Alhassan, I Muhammad, A Idi & Y Abdulmumin · British Journal of Pharmaceutical Research · 2016

Introduction: The rapid increase in the use and consumption of herbal remedies worldwide has been stimulated by several factors, including the notion that most herbal products are safe and effective. Aim: This work was designed to evaluate the acute and subchronic toxicity of ora...

Open access Research Article 10.9734/bjpr/2016/27237

Synthesis of Silver Nanoparticles by Sodium Borohydride Reduction Method: Optimization of Conditions for High Anti-staphylococcal Activity

Ifeanyi Nzekwe, Chukwuma Agubata, Chukwuebuka Umeyor, Ifeanyi Okoye & Chidalu Ogwueleka · British Journal of Pharmaceutical Research · 2016

Aim: The aim of this research was to optimize the reaction conditions for the production of silver nanoparticles sufficiently bioactive for incorporation into pharmaceutical gels. Methods: Silver nanoparticles were prepared by silver nitrate-sodium borohydride reduction method un...

Open access Research Article 10.9734/bjpr/2016/30324

Serum CA19–9 Levels and Pancreatic Beta Cell Destruction in Type 2 Diabetes Mellitus Patients

Mohammad Mansour Saif, Waddaah Al-Asbahy, Abdulkawi Al-Fakih & Adeeb Albadani · British Journal of Pharmaceutical Research · 2016

Carbohydrate antigen 19–9 (CA 19–9) is a tumor–associated antigen, which is used in the diagnosis of pancreatic cancer but is also a marker of pancreatic tissue damage that might be caused by diabetes. The aim of this study was to evaluate serum CA19–9 levels in patients with typ...

Open access Research Article 10.9734/bjpr/2016/30808

Antioxidant Activities and HPLC-DAD Based Phenolic Content Determination of Bauhinia scandens

Md Hossain, Sarzil Niloy, Afroza Hosen, Md Islam, Zahirul Islam, Sajan Das, Md Hassan, A Islam & Md Rana · British Journal of Pharmaceutical Research · 2016

Aim of Study: Bauhinia scandens L. (Leguminosae) is a valuable plant used for various ailments. This study investigated the in vitro antioxidant potential and quantification of selected bioactive plant polyphenol compounds of the ethanolic extracts of Bauhinias scandens (EEBS). S...

Open access Research Article 10.9734/bjpr/2016/31817