Hydrogen bond

Neighboring Nitrogen Atom-Induced Reactions of Azidoacetyl Hydrazides, including Unexpected Nitrogen-Nitrogen Bond Cleavage of the Hydrazide

Hiroki Tanimoto, Ryo Adachi, Aoi Otsuki & Takenori Tomohiro · Organics · 2022

We studied the hydrazide compounds of the α-azidoacetyl group, which showed specific click reactivity by the intramolecular hydrogen bonding between the azido group and the N-H of the hydrazide moiety. In the competitive click reactions with a general alkyl azide, both traceless...

Open access Research Article 10.3390/org3040035

13C NMR Spectroscopic Studies of Intra- and Intermolecular Interactions of Amino Acid Derivatives and Peptide Derivatives in Solutions

Yoshikazu Hiraga, Saori Chaki, Yuri Uyama, Ryosuke Hoshide, Takumi Karaki, Daisuke Nagata, Kanji Yoshimoto & Satomi Niwayama · Organics · 2022

13C NMR spectroscopic investigations were conducted for various amino acid derivatives and peptides. It was observed that 13C NMR chemical shifts of the carbonyl carbons are correlated with the solvent polarities, but the extent depends on the structures. The size of the function...

Open access Research Article 10.3390/org3010003