peripheral tolerance

Tumor Associated Immune Dysfunction: Immune Cells Involved and Suggested Therapies

Wamidh H. Talib & Intisar Hadi AL-Yasari · Annual Research & Review in Biology · 2014

The improvement in the understanding of cancer immunology did not lead to a successful immunotherapeutic strategy. Cancer immunotherapy faces different obstacles including low immunogenicity, production of immunosuppressive agents, and the peripheral tolerance which is used by ca...