Surface modification

Specific Bifunctionalization on the Surface of Phosphorus Dendrimers Syntheses and Properties

Massimo Petriccone, Régis Laurent, Cédric-Olivier Turrin, Rosa Maria Sebastián & Anne-Marie Caminade · Organics · 2022

Dendrimers are highly branched macromolecules possessing, in most cases, identical terminal functions. However, it is sometimes desirable to have two types of surface functions in order to fulfil specific properties. The stochastic functionalization is frequently used for such pu...

Open access Research Article 10.3390/org3030018

Recent Advances in the Synthesis of Piperazines: Focus on C–H Functionalization

Carolina Durand & Michal Szostak · Organics · 2021

Piperazine ranks as the third most common nitrogen heterocycle in drug discovery, and it is the key component of several blockbuster drugs, such as Imatinib (also marketed as Gleevec) or Sildenafil, sold as Viagra. Despite its wide use in medicinal chemistry, the structural diver...

Open access Research Article 10.3390/org2040018

A Sustainable Improvement of ω-Bromoalkylphosphonates Synthesis to Access Novel KuQuinones

Mattia Forchetta, Valeria Conte, Giulia Fiorani, Pierluca Galloni & Federica Sabuzi · Organics · 2021

Owing to the attractiveness of organic phosphonic acids and esters in the pharmacological field and in the functionalization of conductive metal-oxides, the research of effective synthetic protocols is pivotal. Among the others, ω-bromoalkylphosphonates are gaining particular att...

Open access Research Article 10.3390/org2020010