Trimethylsilyl

The Regio- and Stereoselective Synthesis of 1,4-Diarylbut-1-en-3-ynes Having Aryl Groups at the Mutual Syn Positions

Szymon Rogalski, Natalia Szymaszek & Cezary Pietraszuk · Organics · 2023

(E)-1-aryl-2,4-bis(trimethylsilyl)but-1-en-3-ynes readily undergo protodesilylation and subsequent aerobic, copper-free Sonogashira cross-coupling with aryl halides to form (E)-1,4-diaryl-2-(trimethylsilyl)but-1-en-3-ynes. The proposed one-pot, two-step approach allows access to...

Open access Research Article 10.3390/org4020017

Esterifications with 2-(Trimethylsilyl)ethyl 2,2,2-Trichloroacetimidate

Wenhong Lin, Shea Meyer, Shawn Dormann & John Chisholm · Organics · 2021

2-(Trimethylsilyl)ethyl 2,2,2-trichloroacetimidate is readily synthesized from 2-trimethylsilylethanol in high yield. This imidate is an effective reagent for the formation of 2-trimethylsilylethyl esters without the need for an exogenous promoter or catalyst, as the carboxylic a...

Open access Research Article 10.3390/org2010002

Understanding the Reactivity of Trimethylsilyldiazoalkanes Participating in [3+2] Cycloaddition Reactions towards Diethylfumarate with a Molecular Electron Density Theory Perspective

Luis Domingo, Nivedita Acharjee & Haydar Mohammad-Salim · Organics · 2020

A Molecular Electron Density Theory (MEDT) study is presented here for [3+2] cycloaddition (32CA) reactions of three trimethylsilyldiazoalkanes with diethyl fumarate. The presence of silicon bonded to the carbon of these silyldiazoalkanes changes its structure and reactivity from...

Open access Research Article 10.3390/org1010002