tuberculosis

Analyzing Different Acetyl Co-A Metabolizing Enzymes as Potential Drug Targets against Mycobacterium tuberculosis

Shamim Akhtar, Sheetal Singh, Santosh Kumar & Dhiman Sarkar · Microbiology Research Journal International · 2015

Mycobacterium tuberculosis, the causative agent of tuberculosis, is responsible for the deaths of million people around the globe. The scenario is worse than ever due to the emergence of drug resistant strains which are widely spread throughout the globe in much faster ways. To c...

Open access Research Article 10.9734/BMRJ/2015/19032

Changes in Serum Levels of TNF-α & IL-4 among New, Under-treatment & MDR TB Patients

Nazish Fatima, Mohammad Shameem, Nabeela . & Haris M. Khan · Microbiology Research Journal International · 2015

Introduction: Tuberculosis (TB) remains a significant public health problem with an estimated one-third of the world’s population being infected. Cytokines play a major role in protection against Mycobacterium tuberculosis infection and regulate the immune responses at cellular l...

Open access Research Article 10.9734/BMRJ/2015/14798

In silico Structural Characterization of Rv3473c from Mycobacterium tuberculosis H37Rv: Potentials in Drug Development

Nurul Islam, Giasuddin Ahmed & Vishal Trivedi · Microbiology Research Journal International · 2015

Aims: Large proportion of Mycobacterium tuberculosis H37Rv proteome still needs to be characterized especially peroxidase proteins as drug targets. There is twenty (20) known peroxidases that have been annotated in the genome. Among these Rv3473c has been studied by us using suit...

Open access Research Article 10.9734/BMRJ/2015/15005