uric acid

Ten Years Milestones in Xanthine Oxidase Inhibitors Discovery: Febuxostat-Based Inhibitors Trends, Bifunctional Derivatives, and Automatized Screening Assays

Miguel F. S. de Abreu, Camila A. Wegermann, Millena S. Ceroullo, Isabella G. M. Sant’Anna & Renato C. S. Lessa · Organics · 2022

Xanthine oxidase (XO) is an enzyme involved in the oxidative process of hypoxanthine and xanthine to uric acid (UA). This process also produces reactive oxygen species (ROS) as byproducts. Both UA and ROS are dangerous for human health, and some health conditions trigger upregula...

Open access Research Article 10.3390/org3040026

Prognostic use of Prostate Specific Antigen, Some Renal Indices and Uric Acid in the Diagnosis of Prostate Cancer and Renal Impairment at Urology Clinic Federal Medical Centre Lokoja, Nigeria

Isaac Paul Emeje, Nkiruka Rose Ukibe, Nwakasi K. Nnamah, Charles Chinedum Onyenekwe, Solomon Nwabueze Ukibe, Emmanuel Ikechukwu Onwubuya, Obiageli Fidelia Emelumadu, Ifeoma Nwamaka Monago & Friday Alfred Ehiaghe · Annual Research & Review in Biology · 2018

Aims: Improved diagnosis of prostate cancer has led to increasing life expectancy in adult men. The use of PSA as the current practice for screening and treatment has become a key prognostic factor in the management of PCa. This study was designed to evaluate the prognostic use o...

Open access Research Article 10.9734/ARRB/2018/42389