Background: Malaria during pregnancy remains a major public health challenge in sub-Saharan Africa and is associated with maternal anemia, adverse fetal outcomes, and immune alterations. Changes in leukocyte distribution reflect host immune responses and may provide insight into...
Open access
Research Article10.9734/ijrrgy/2026/v9i1159
Background: Pregnancy induces coordinated hematologic adaptations to sustain maternal–fetal oxygen exchange. While clinical assessment traditionally relies on red cell indices such as hemoglobin concentration, hematocrit, and mean corpuscular volume, these static measures incompl...
Open access
Research Article10.9734/ijr2h/2026/v9i1216
Background: Sickle cell disease (SCD) is classically defined by a single-point mutation in the β-globin gene leading to hemoglobin S polymerization and erythrocyte sickling. However, accumulating evidence indicates that SCD is a complex multisystem disorder characterized by chron...
Open access
Research Article10.9734/ijr2h/2026/v9i1212
Emmanuel I. Obeagu, Precious Omotunde, Getrude Uzoma Obeagu, Richard I. Eze, Ukamaka Edward, Chukwum J. Okafor, C. C. N. Vincent, Ejike Felix Chukwurah & Blessing Oluchi Akalonu·Journal of Pharmaceutical Research International·2021
Background: Obesity is a serious health problem, it increases heart-related diseases and its prevalence continues to increase due to genetic and lifestyle influences. This study aims to evaluate the hematological parameters of obese individuals based on gender in the Omisanjana r...
Open access
Research Article10.9734/jpri/2021/v33i43A32500
Emmanuel I. Obeagu, Quratulain Babar, Immaculata Ogochukwu Uduchi, Adaobi Maryann Ibekwe, Udunma Olive Chijioke, Chukwum J. Okafor & C. C. N. Vincent·Journal of Pharmaceutical Research International·2021
Recipients' immune systems are triggered by blood and blood component therapy. Transfusion-related immunomodulation (TRIM) is a complicated immunological response to transfusion that results in immunosuppression. The mechanisms of TRIM include the presence of residual white blood...
Open access
Research Article10.9734/jpri/2021/v33i42A32394
Emmanuel I. Obeagu, Quratulain Babar, C. C. N. Vincent, Chukwum J. Okafor, Richard Eze, Udunma Olive Chijioke, Adaobi Maryann Ibekwe & Immaculata Ogochukwu Uduchi·Journal of Pharmaceutical Research International·2021
Severe Acute Respiratory Syndrome Coronavirus 2 is a new type of coronavirus that can cause Coronavirus Disease 2019 (Covid-19) and is associated with an increased risk of thrombosis-related pulmonary embolism. Globally, doctors have revised their management strategies for suspec...
Open access
Research Article10.9734/jpri/2021/v33i42A32388
This study was aimed at evaluating the serum levels of Calcium, Inorganic phosphate and Magnesium together with the Body Mass Index (BMI) in lactating mothers in Owerri. A total of sixty subjects were recruited. Thirty were lactating subjects while thirty were apparently healthy...
Open access
Research Article10.9734/jpri/2021/v33i41B32360
I. L. Okoroiwu, Emmanuel I. Obeagu, Lilian Nneka Egbuobi, Adaobi Maryann Ibekwe, C. C. N. Vincent, Bright Chukwuebuka Unaeze, Calista Ndidi Adike, Udunma Olive Chijioke, Chukwuma J. Okafor, Ayomide Olusiji Soremi, Ejike Felix Chukwurah, Bart I. Ifionu & Confidence Ogechi Anyanwu·Journal of Pharmaceutical Research International·2021
The values of factor VIII (FVIII) and factor IX (FIX) were evaluated among some primary school children in Owerri zone Imo State. The aim was to assess deficiency state or reduction in activity among these children. A total of two hundred and ten (210) venous blood samples were c...
Open access
Research Article10.9734/jpri/2021/v33i34B31864
Arvin Nwakulite, Emmanuel I. Obeagu, Richard Eze, Valerie Esame Ugochi, C.C.N. Vincent, Chukwuma J. Okafor, Ejike Felix Chukwurah, Bright Chukwuebuka Unaeze, Chukwudi Ofodile Amaechi, Chetachi Blessing Okwuanaso, Ufuoma Chukwuani & Bart I. Ifionu·Journal of Pharmaceutical Research International·2021
Diabetes mellitus (DM) is a metabolic disease in which there are high blood sugar levels. Type 2 is due to the cells of the body not responding properly to the insulin produced. The aim of this study was to evaluate the enzyme activity in glutathione peroxidase in type 2 diabetic...
Open access
Research Article10.9734/jpri/2021/v33i30B31655
Arvin Nwakulite, Emmanuel I. Obeagu, Richard Eze, C. C. N. Vincent, Ejike Felix Chukwurah, Chukwuma J. Okafor, Adaobi Maryann Ibekwe, Calista Ndidi Adike, Ufuoma Chukwuani & Bart I. Ifionu·Journal of Pharmaceutical Research International·2021
This study was carried out to evaluate catalase and manganese in type 2 diabetes mellitus patients. A total of 40 subjects Were included in this study. This comprised of equal number of male and female subjects respectively. Enzyme linked immunosorbent assay (ELISA) method was us...
Open access
Research Article10.9734/jpri/2021/v33i30B31638
Richard Eze, Emmanuel I. Obeagu, Arvin Nwakulite, I. L. Okoroiwu, C. C. N. Vincent, Chukwuma J. Okafor, Ejike Felix Chukwurah, Udunma Olive Chijioke & Chukwudi Ofodile Amaechi·Journal of Pharmaceutical Research International·2021
Copper is an essential trace mineral (micronutrient) that is naturally present in some foods and is available as a dietary supplement. Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.This study was desiged to assay the co...
Open access
Research Article10.9734/jpri/2021/v33i30A31616
Richard Eze, Emmanuel I. Obeagu, Arvin Nwakulite, C.C.N. Vincent, Sylvester Ogbonna Ogbodo, Adaobi Maryann Ibekwe, Chukwuma J. Okafor & Ejike Felix Chukwurah·Journal of Pharmaceutical Research International·2021
Haemoglobin genotype variants, ABO and Rh blood groups are known to vary from one population to another. Standard electrophoretic and haemagglutination techniques were employed in testing the blood samples. Of the 150 test subjects screened, HbAA in the male subjects were 58(48....
Open access
Research Article10.9734/jpri/2021/v33i29B31600
Background: High malaria burden has led to the increase use of insecticides in the tropics and subtropics. This study thus aimed at assessing the effect of insecticides inhalation on haemorrheological parameters using experimental animal model. Materials and Methods: Sixteen adul...
Preeclampsia is a serious and life-threatening pregnancy complication. In this study, the levels of inflammatory cytokines were measured in preeclamptic women in Owerri, Imo State. A total of 120 pregnant women aged 18-45 years at 20-40 weeks of pregnancy were recruited; 60 were...
Open access
Research Article10.9734/jpri/2021/v33i42A32384
Chekwube Catherine Agu, C. N. Onwasigwe, Emmanuel I. Obeagu, C. C. N. Vincent, Udunma Olive Chijioke, Calista Ndidi Adike, Chukwum J. Okafor, Adaobi Maryann Ibekwe, Lizzy Agunwah & Confidence Ogechi Anyanwu·Journal of Pharmaceutical Research International·2021
Background: Immunization is the process by which a person’s immune system is fortified and made resistant to an infectious disease/ agent. Immunization saves millions of lives. It is the most important means of preventing childhood morbidity and mortality. This study investigated...
Open access
Research Article10.9734/jpri/2021/v33i39B32174
Chukwum J. Okafor, Bart I. Ifionu, Ufuoma Ohwo, Nkem F. Obianagha, Emmanuel I. Obeagu, Omobolanle Abioye Ogundahunsi, E. N Adejumo & Seyi Samson Enitan·Journal of Cancer and Tumor International·2025
Introduction: Prostatic diseases, including prostate cancer (CAP) and benign prostatic hyperplasia (BPH), are prevalent pathologies in ageing men. While prostate-specific antigen (PSA) is a well-established diagnostic marker, the role of serum testosterone in distinguishing betwe...
Open access
Research Article10.9734/jcti/2025/v15i4328
Bart I. Ifionu, Chukwum J. Okafor, Ufuoma Ohwo, Nkem F. Obianagha, Emmanuel I. Obeagu, Omobolanle Abioye Ogundahunsi, E. N Adejumo & Seyi Samson Enitan·Journal of Cancer and Tumor International·2025
Background: Vitamin A and D are both fat-soluble vitamins that are crucial for maintaining overall health and are highly indispensable, despite their minimal daily requirements. Their involvement in cell proliferation, differentiation, and apoptosis has linked them to the develop...
Open access
Research Article10.9734/jcti/2025/v15i3311
Chukwuma J. Okafor, Said A. Yusuf, Salma A. Mahmoud, Salum S. Salum, Sonia C. Vargas, Adu E. Mathew, Emmanuel I. Obeagu, Husna K. Shaib, Hashima A. Iddi, Masoud S. Moh’d & Warda S. Abdulrahman·Journal of Pharmaceutical Research International·2021
Diabetes type 2 (T2D) had caused the loss of millions of lives all over the world. About 50% of the patients with T2D die because of cardiovascular disease (CVD), primarily myocardial infarction and stroke. Many of the leading risk factors for CVD coexist and act synergistically...
Open access
Research Article10.9734/jpri/2021/v33i29B31591
Rodolfo Isidro Bosch Bayard, Kenechukwu M. Okafor, Chukwum J. Okafor, Diane Millo Martin, Othman Said Abdalla, Lorena Bosch Orihuela, Aniuska Palacios Noa & Emmanuel I. Obeagu·International Neuropsychiatric Disease Journal·2025
Introduction: Mental illness imposes a significant global health burden, often compounded by stigma that hinders care. Medical students, as future healthcare providers, play a crucial role in shaping perceptions of mental health and service delivery. Understanding their attitudes...
Open access
Research Article10.9734/indj/2025/v22i5516
Rodolfo Isidro Bosch Bayard, Kenechukwu M. Okafor, Chukwum J. Okafor, Diane Millo Martin, Othman Said Abdalla, Lorena Bosch Orihuela, Aniuska Palacios Noa & Emmanuel I. Obeagu·International Neuropsychiatric Disease Journal·2025
Introduction: Mental illness poses a significant global health burden. Medical students, as future healthcare providers, play a crucial role in mental health service delivery, making their knowledge and attitudes toward mental illness essential for improving healthcare outcomes....
Open access
Research Article10.9734/indj/2025/v22i4508