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G. S. N. Koteswara Rao

Publications (4)

Response Surface Methodology Driven Systematic Development of a Stability- indicating RP-UPLC Method for the Quantification of Aliskiren: A Renin Inhibitor

Bikash Ranjan Jena, G. S. N. Koteswara Rao, Rajasekhar Reddy Alavala, Prasanna Kumar Desu, G. Chakravarthi, Suryakanta Swain, Debi Prasad Pradhan & P. Niharika · Journal of Pharmaceutical Research International · 2021

Aims: The current study envisages experimental design enabled rapid, sensitive, and stability-indicating RP-UPLC method to quantify Aliskiren in its pharmaceutical formulations. Study Design: Box-Benkhen experimental Design using Response surface methodology. Place and Duration o...

Open access Research Article 10.9734/jpri/2021/v33i52B33617

Hepatoprotective Activity of Acampe praemorsa

Praveen Kumar Uppala, G. S. N. Koteswara Rao, A. Rajasekhar Reddy, K. Umasankar, C. Joshitha, Kanagala Anusha, Nadeem Siddiqui & Sarada Prasanna Mallick · Journal of Pharmaceutical Research International · 2021

Introduction: Liver is one of major functional organ in body, its damage can alter body metabolisms and other organs’ function. So, it is very important to maintain the healthy liver. Now a days, different chemicals and inadequate use of medicines are causing liver impairments in...

Open access Research Article 10.9734/jpri/2021/v33i30A31627

Clinical Features, Diagnosis and Treatment Strategies of Limb Girdle Muscular Dystrophy: An Observational Study from South India

S. Nigama Chandra, A. Anka Rao, G. S. N. Koteswara Rao, K. Umasankar & A. Rajasekhar Reddy · Journal of Pharmaceutical Research International · 2021

Objective: The present observational study describes the natural course of clinical features, family history, and diagnosis pattern and treatment strategies in rare genetic disorder, Limb girdle muscular dystrophy (LGMD). Research Design: Observational study Methods: Clinically/I...

Open access Research Article 10.9734/jpri/2021/v33i44A32610

Stability Indicating RP-HPLC Method for the Analysis of Dacomitinib and its Related Impurities in Bulk and Oral Solid Dosage Formulations

Venu Kamani, M. Sujatha, G. S. N. Koteswara Rao & N. Vinod Kumar · Journal of Pharmaceutical Research International · 2021

Dacomitinib is an epidermal growth factor receptor inhibitor prescribed for the treatment of metastatic non small-cell lung carcinoma. There are no reported significant official of HPLC methods that resolve the impurities and degradation products generated during stability studie...

Open access Research Article 10.9734/jpri/2021/v33i40B32278