Joseph Aondowase Orkuma, Julie Ochaka Egesie, Simji Samuel Gomerep & Ejele Osaikhuemen Adebayo·Asian Hematology Research Journal·2018
Background: Global targets of providing safe blood available universally by 2020 as well as that seeking to eliminate HIV transmission by 2030 has compelled many hospital-based blood banks to employ relevant strategies in their transfusion practice towards realizing these targets...
Introduction: von Willebrand Factor (VWF) plays a vital role in platelet aggregation. The unusually large VWF multimers mediate the adhesion of sickle red blood cell (RBC) to endothelial cells and contribute to vaso-occlusive episodes. Objective: The aim of this study was to dete...
The aim of this investigation is to determine tHcy levels in SCD Omani Arabs in (i) the steady state (ii) crisis (iii) relative to non-SCD subjects as such values might help clarify the role of tHcy in SCD. Serum tHcy concentrations and other laboratory analyses including serum...
Background: The degree of platelet activation may be assessed by platelet indices such as platelet count (PC), mean platelet volume (MPV) and platelet distribution width (PDW). Platelet indices are potentially predictive, diagnostic and prognostic useful markers for platelet-rela...
B. Chetcha Chemegni, A. V. Kouam Kaping, I. Ngosso Tetanyé, A. Bodieu Kenmegne, L. Kouemeni, G. Ngouefo, E. K. Ola Bamzok, Tetanye Ekoe & L. Kaptué Noche·Asian Hematology Research Journal·2018
Sickle cell disease is the most frequent genetic disease worldwide with high mortality and morbidity rates. Several therapeutic medications have been put in place amongst which hydroxurea, an antineoplastic for which the clinical-biologic benefits for the patients have been estab...
Though concerns over the safety of medicinal drugs are following rife consumption of some herbal preparations, the underlying pathogenesis remains however cryptic. Awareness of the far-reaching effects of herbal preparations is germane to their continued use in traditional medici...
The hematological indices namely erythrogram is an important parameter for evaluating human’s physiological status. I can vary accordingly depending upon the differential traits (Asian, Arabian, European … etc), sex, age, and health condition. In best of our knowledge, due to lac...
Nya Nkwikeu Prudence Josela, Biapa Nya Prosper Cabral, Chetcha Bernard, Yembeau Lena Natacha, Kengne Fotsing Christian Bernard & Pieme Constant Anatole·Asian Hematology Research Journal·2018
Background: SCA is a systemic disease which affects more than 50 million people in the world. The gene mutation results in the cause of the synthesis of abnormal haemoglobin S (HbS) which is a pro-oxidant machine and induces ROS production. In addition, sickle cell patients are d...
Kengne Fotsing Christian Bernard, Biapa Nya Prosper Cabral, Chetcha Bernard, Nguelewou Lemlon Flora, Pieme Constant Anatole & Gatsing Donatien·Asian Hematology Research Journal·2018
Sickle cell anaemia is a hereditary blood disease characterized by the presence of haemoglobin S in red blood cells. It affects over 2 million people in Cameroon. Haemoglobin S can induce the oxidative stress and changes in electrolyte level in patients. The aim of this study was...
Aim: This study aimed at evaluating the red cell indices of children seen at the Federal Medical Centre, Azare, Nigeria, with a view to determining their utility in the diagnosis of severe malaria. Study Design: The study was a case control study. Place and Duration of the study:...