Isoniazid is an important first-line antituberculosis drug; however, its administration may induce oxidative stress and hepatic biochemical disturbances. This study evaluated the effects of nutraceutical antioxidants and functional foods on isoniazid-induced oxidative stress and...
Open access
Research Article10.9734/ajrrhe/2026/v8i167
Background: Diabetes mellitus is frequently accompanied by hepatic dysfunction, dyslipidaemia, and impaired protein metabolism, which contribute substantially to disease progression and cardiovascular risk. Although Moringa oleifera and Tamarindus indica possess documented antidi...
Open access
Research Article10.9734/ajrrhe/2026/v8i166
Background: Budd–Chiari syndrome (BCS) results from hepatic venous outflow obstruction and is rarely associated with external compression by hepatic hydatid cysts. Small cysts at the hepatic dome may cause early venous indentation before thrombosis or classical radiological featu...
Open access
Research Article10.9734/ajrrhe/2026/v8i165
Doxorubicin is an effective anticancer drug, but its clinical use may be limited by tissue toxicity, including liver injury. This study evaluated the acute toxicity profile and possible hepatoprotective effect of ethanol seed extract of Persea americana in doxorubicin-induced mal...
Open access
Research Article10.9734/ajrrhe/2026/v8i164
Background: Primary biliary cholangitis is a chronic autoimmune cholestatic liver disease that predominantly affects women; however, male patients may present with delayed recognition and more advanced disease. Data on primary biliary cholangitis in men remain limited in North Af...
Open access
Research Article10.9734/ajrrhe/2026/v8i163
Background: Seronegative primary biliary cholangitis (snPBC) is an uncommon variant of PBC in which characteristic antimitochondrial antibodies are absent despite clinical, biochemical, and histological features consistent with the disease. The lack of serological markers may del...
Open access
Research Article10.9734/ajrrhe/2026/v8i162
Background: Malignant biliopancreatic strictures are a major cause of obstructive jaundice and are frequently associated with advanced pancreatic and biliary malignancies. Endoscopic retrograde cholangiopancreatography (ERCP) with biliary drainage remains the preferred palliative...
Open access
Research Article10.9734/ajrrhe/2026/v8i161
Hepatitis A virus (HAV) infection is a common cause of acute viral hepatitis in children and usually follows a benign, self-limited course (Schiff, 1992, Wang et al., 2015, Tong et al., 1995). However, atypical manifestations are increasingly recognized, and prolonged cholestatic...
Open access
Research Article10.9734/ajrrhe/2026/v8i160
Background: Obstructive jaundice is a common hepatobiliary disorder characterized by impaired bile flow and cholestasis, leading to significant morbidity if not promptly treated. Gamma-glutamyl transferase (GGT) and alkaline phosphatase (ALP) are key cholestatic liver enzymes wid...
Open access
Research Article10.9734/ajrrhe/2026/v8i159
Ransford Oduro Kumi, Belinda Oti, Andrews Kumi, Erica Morvey Mawulorm, Gloria Donkor, Ampomah Abena Asante, Emmanuel Ayitey, Rita Oforiwaa Aygeman Ntim, Sefakor Adzo Agbenyegah & Isaac Kporha·Asian Journal of Research and Reports in Hepatology·2025
Background: Neonatal jaundice is a major contributor to neonatal morbidity and mortality in sub-Saharan Africa. Understanding its determinants is vital for improving neonatal outcomes. This study assessed the prevalence and determinants of this public health challenge in two hosp...
Open access
Research Article10.9734/ajrrhe/2025/v7i158