Background: Glioblastoma Multiforme (GBM) presents significant diagnostic and therapeutic challenges due to its complex molecular pathogenesis. Current diagnostic methods often fail to detect early molecular signatures critical for timely intervention. This study integrates micro...
Open access
Research Article10.9734/ajorrin/2025/v9i1161
Introduction: Precision neurorehabilitation represents a fundamental paradigm shift away from standardized, protocol-driven treatment toward dynamically adaptive therapies tailored to the unique biological and functional profiles of individual patients. The recognized high degree...
Open access
Research Article10.9734/ajorrin/2025/v8i1160
Background: Osmotic Demyelination Syndrome (ODS) is a rare neurological disorder typically linked to rapid correction of hyponatremia, but its occurrence due to hypernatremia, especially in the postpartum period, is exceedingly uncommon. Case Presentation: A 23-year-old woman, 14...
Open access
Research Article10.9734/ajorrin/2025/v8i1159
Aim: Investigate the neuroprotective effects of ethanolic extract of Aloe vera (EEAV) on mercury chloride-induced damage in the amygdala and hippocampus of adult male Wistar rats, using histological and molecular docking approaches. Study Design: 35 rats were randomly assigned in...
Open access
Research Article10.9734/ajorrin/2025/v8i1158
Aim: Cerebral palsy (CP) remains the most common cause of chronic childhood disability worldwide. In Nigeria, there is a need to provide updated information to establish current clinical trends. This study described the clinical characteristics of children diagnosed with cerebral...
Open access
Research Article10.9734/ajorrin/2025/v8i1157
Objective: To gather clinicians' perspectives on the clinical use of the combination therapy of pregabalin and nortriptyline for neuropathic pain in Indian settings. Methodology: This cross-sectional study utilized a multiple-response questionnaire comprising 23 questions designe...
Open access
Research Article10.9734/ajorrin/2025/v8i1156
Background: Albinism, a genetically inherited condition characterised by the partial or complete absence of melanin, remains poorly understood and stigmatised in many African societies, including Nigeria. Individuals with albinism often experience discrimination, social exclusion...
Open access
Research Article10.9734/ajorrin/2025/v8i1155
Background: Substance use has become a significant public health issue, particularly among the youth population, with 1 in 20 to 1 in 5 people aged 15 years and above reported to be involved in substance use. This has been linked with several factors, including socio-economic an...
Open access
Research Article10.9734/ajorrin/2025/v8i1154
Background: Hallervorden-Spatz Disease (HSD), an aggressive and rare form of Neurodegeneration with Brain Iron Accumulation (NBIA), has specific rehabilitation issues in its rapid neurodegenerative course and early loss of motor milestones. Physiotherapy literature still lacks th...
Open access
Research Article10.9734/ajorrin/2025/v8i1153
Introduction: Hemangiomas are vascular tumors that are not malignant and arise from the aberrant growth of blood vessels. Primary CNS tumors can occur in any part of the central nervous system, including the brain and spinal cord Aim: The aim of this case report is to emphasize t...
Open access
Research Article10.9734/ajorrin/2025/v8i1152