Background: Heavy metal toxicity, particularly from lead exposure, poses significant neurodevelopmental risks, with the cerebellum being a key target. This study evaluated the ameliorative potential of a phytobiotic formulation comprising aqueous extracts of Zingiber officinale (...
Open access
Research Article10.9734/ajorrin/2025/v8i1141
Children with neurodevelopmental disorders (NDDs) often face marked difficulties in initiating and sustaining purposeful, goal-directed behaviour. These difficulties are usually attributed to conative deficits—a critical domain of human development that governs motivation, voliti...
Open access
Research Article10.9734/ajorrin/2025/v8i1140
Background and Aims: Artequin, a commonly used artemisinin-based antimalarial therapy, has been associated with central nervous system side effects, yet its effects on hippocampal–cerebellar function remain unclear. This study investigated it neurohistochemistry, immunoreactivity...
Open access
Research Article10.9734/ajorrin/2025/v8i1139
Rumination, characterized by excessive repetitive and perseverative thinking about negative experiences and emotions, represents a transdiagnostic feature across multiple psychiatric disorders including major depressive disorder (MDD), anxiety disorders, post-traumatic stress dis...
Open access
Research Article10.9734/ajorrin/2025/v8i1138
Background: Internuclear ophthalmoplegia (INO) is generally caused by a lesion in the medial longitudinal fasciculus, characterised by diminished adduction and contralateral abduction nystagmus. Reverse INO, or "INO of abduction," is a rare variation, often linked to elevated int...
Open access
Research Article10.9734/ajorrin/2025/v8i1137
Oresanya M.E, Ehiremen S.E, Alabi A.O, Adejinmi S.O, Abdusalam M.K, Adelakin L.A, Taiwo-Ola D.O, Banjo T.A, Amballi A.A, Shallie P.D & Fakunle P.B·Asian Journal of Research and Reports in Neurology·2025
5-Fluorouracil (5-FU) is a widely used chemotherapeutic agent known for its neurotoxic side effects, including oxidative stress and behavioral disturbances. This study investigated the neuroprotective potential of Nigella sativa oil (NSO), a natural antioxidant, against 5-FU-indu...
Open access
Research Article10.9734/ajorrin/2025/v8i1136
Background: A cerebrovascular accident (stroke) is a medical emergency that can lead to irreversible brain damage or death. It is a cause of disability and poor quality of life among the paediatric population. This study aims to determine the clinical features and aetiology of st...
Open access
Research Article10.9734/ajorrin/2025/v8i1135
Introduction: Sleep is one of man's primary needs. The quality of sleep improves well-being and consequently the performance of humans in their various activities. The aim of this study was to evaluate the prevalence and determining factors of sleep disorders among health profess...
Open access
Research Article10.9734/ajorrin/2025/v8i1134
Introduction: Oxidative stress and increased reactive oxygen species have been implicated in recurrent seizures, but selenium containing glutathione peroxidase are reported to protect against oxidative damage and promote neuronal cell survival. Aim: We compared levels of seleni...
Open access
Research Article10.9734/ajorrin/2025/v8i1133
Background and Objectives: Cadmium is a potent neurotoxic heavy metal known to induce oxidative stress, apoptosis, and neurotransmitter dysfunction, leading to neurodegenerative effects. Turmeric (Curcuma longa) has gained attention as a natural antioxidant with potential neuropr...
Open access
Research Article10.9734/ajorrin/2025/v8i1132