Immune checkpoint inhibitors have made a drastic improvement in the management of cancer though it is not completely free from adverse outcomes, which may be due to the dysregulated immune system. These negative outcomes following treatment with checkpoint inhibitors are collecti...
Open access
Research Article10.9734/ijmpcr/2025/v18i2414
Metformin is one of the most commonly prescribed oral antihyperglycemic medicine worldwide. Professional diabetes organizations recommend it as the first-line treatment for newly diagnosed type 2 diabetes. Metformin is widely regarded as safe. The most common side effects include...
Open access
Research Article10.9734/ijmpcr/2025/v18i1413
Aim: Guillain-Barré Syndrome (GBS) is an autoimmune disorder of the peripheral nervous system that often presents with progressive limb weakness and sensory disturbances. Globally, the incidence rate of Guillain-Barré Syndrome (GBS) is approximately 0.001% to 0.002% of the popula...
Open access
Research Article10.9734/ijmpcr/2025/v18i1412
The purpose of the study is to present a complicated case who present an unwanted severe headache which occur in a patient receiving a spinal or epidural injection. We report the case of a 64-year-old male patient who underwent skin transplantation, namely split-thickness skin gr...
Open access
Research Article10.9734/ijmpcr/2025/v18i1411
Aim: Dengue fever is a major health risk in endemic regions, and its complications can be severe in individuals with underlying haematological conditions like sickle cell anaemia (SCD). SCD increases the risk of Vaso-occlusive crises, haemolysis, and multi-organ dysfunction, whic...
Open access
Research Article10.9734/ijmpcr/2025/v18i1410
Neuromyelitis optica spectrum disorder, formerly known as neuromyelitis optica or Devic's disease, affects roughly 0.3 to 4.4 individuals per 100,000. NMOSD is a peculiar inflammatory disease of the central nervous system that manifests clinically as optic neuritis, transverse my...
Open access
Research Article10.9734/ijmpcr/2025/v18i1409
This case report highlights the use of intravenous high-dose Epoprostenol for managing severe digital ischemia in a patient diagnosed with antisynthetase syndrome (ASyS) exhibiting anti-Jo1 antibodies positivity, emphasizing its vasodilatory benefits and challenges with tolerabil...
Open access
Research Article10.9734/ijmpcr/2025/v18i1408
The tapetal-like reflex (TLR) is a rare, golden, bright, scintillating, particulate reflection observed during indirect ophthalmoscopy, typically sparing the fovea. It resembles the reflection seen in the eyes of certain vertebrates. TLR has been noted in female carriers of X-lin...
Open access
Research Article10.9734/ijmpcr/2025/v18i1407
The purpose of the study is to present a complicated case who present a very rare retinal viral infection masqued initially by intravitreal hemorrhage. We report the case of a 24-year-old patient with chronic asthma on inhaled beta-2 mimetics and corticosteroids who had been pres...
Open access
Research Article10.9734/ijmpcr/2025/v18i1406
Pilocytic astrocytoma (PA) is the most common juvenile cerebellar tumor and glial neoplasm of the central nervous system, typically diagnosed in children and young adults. Characterized by benign, low-grade, slow-growing tumors, PA has a favorable prognosis, with a 94% survival r...
Open access
Research Article10.9734/ijmpcr/2024/v17i4405