Lawrence John AJutor, Blessing Aitebiereme Iyoyojie, Kingsley Ugonna Ugoagwu, Orkaa Terungwa Samuel, Olufemi Adesola Adedayo, Daniel Temiloluwa Oyedemi, Daniel Ebubechi Obasi, Adegbesan Abiodun Christopher, Adewoyin Peter Bemigho & Christian Ajiri Adobor·International Research Journal of Oncology·2025
Triple-negative breast cancer (TNBC) is one of the most prominent types of breast cancer. It is a very aggressive subtype that is characterized by the absence of certain receptors which are expected on the surface of tumor cells. Limited treatment options and a poor prognosis, hi...
Open access
Research Article10.9734/irjo/2025/v8i1170
Background: Primary adenoid cystic carcinoma (ACC) of breast is rarely seen clinically. It is a special subtype of triple-negative breast cancer characterized by low expression of Ki-67, low malignant potential, slow progression and favourable prognosis. To date, treatment for th...
Open access
Research Article10.9734/irjo/2025/v8i1169
Immunotherapy has emerged as a transformative approach in cancer treatment, yet its efficacy is often limited by interpatient variability and immune resistance mechanisms. Recent advances suggest that nutritional status and dietary interventions can significantly influence the im...
Open access
Research Article10.9734/irjo/2024/v7i2168
Background: T-PLL is a rare T cell Chronic Lymphoproliferative disorder (T-CLPD), representing about 2% of mature lymphocytic leukaemia in adults over age of 30 years, with a median diagnosis age of 65 years. It commonly presents with symptoms like hepatosplenomegaly, generalized...
Open access
Research Article10.9734/irjo/2024/v7i2167
Jane Nkechi Nwafor, Taiwo A Falaiye, Olubukola Anike Kuye, Simbiat Quadri Eniola, Ehireme Anne Osarenkhoe-Ighodaro, Kelechi Ethelbert Oguzie, Okelue E. Okobi & Maurice Puomaaye Konta·International Research Journal of Oncology·2024
Primary care plays a vital role in cancer patients' early detection, referral, and ongoing management. This systematic review explores how primary care providers (PCPs) facilitate early diagnosis, ensure continuity of care, and support patients throughout their cancer journey and...
Open access
Research Article10.9734/irjo/2024/v7i2165
Fenny Halim, Slamet Isworo, Enny Rachmani, Teguh Suryanto, Fitri Amalia, Grestaliansa Indira & Muhammad Faiq Malik Al Hakim·International Research Journal of Oncology·2024
Background and Objective: The management of Papillary Thyroid Carcinoma (PTC) is influenced by factors such as patient age and clinical characteristics. However, the clinical features of PTC in adolescents (ages 10-19) have not been widely studied. Adolescents may present unique...
Open access
Research Article10.9734/irjo/2024/v7i2166
Soft tissue tumors are a diverse range of diagnostic entities including the majority of them benign in nature and behavior. Soft tissue sarcomas are uncommon tumors that represent 1% of all malignancies and are classified as malignant entities. The wide variety of tumor types and...
Rita Nkiru Ajirenike, Amaewhule Mary Nnneda, Dasetima D. Altraide, Figilo Ibeinmo Moses, Amadi Ekechi Stella, Johnson Mine & Ogbu Christian.·International Research Journal of Oncology·2024
Kaposi sarcoma (K.S) is a rare type of cancer with four clinical variants which has a link to Human Herpes Virus (HHV-8) in the etiology. Commonly seen are the acquired immunodeficiency syndrome (AIDS) -related variants. Kaposi Sarcoma occurring after solid-organ transplant is a...
Samuel Chukwuemeka Okenwa, Lazarus Chukwuemeka Ejike, Ifunanya Genevieve Anunwa, Jane Chidera Nwachukwu, Wisdom Joe Igbokwe, Henry Chiagozie Igwenagu, Emmanuel Buchi Onyioha, Joel Chekwube Ugwuezea & Chika Augusta Ekweozor·International Research Journal of Oncology·2024
Background: Cancer is currently a global health issue and has claimed the lives of many. Cancer used to be a previously more prevalent in high-income countries, but at the moment, 75% of new cancer cases could be from low and middle income countries (LMIC). Healthcare workers pl...
Colorectal cancer (CRC) is the third most common cancer worldwide, remains a major cause of cancer-related morbidity and mortality globally. It has diverse treatment modalities including chemotherapy, immunotherapy, and targeted therapies. Chemotherapy remains a cornerstone of CR...