This review is intended to take us through a journey on how cancer had been treated and highlight the paradigm shift in understanding its treatment since adoption of evolution concept and hope to point to a possible future breakthrough in cancer management. Researchers estimate t...
Open access
Research Article10.9734/JCTI/2016/27710
Aims: To evaluate the Activated Partial Thromboplastin Time (APTT) and fibrinogen levels in patients with Polycythemia vera (PV). Study Design: Analytical, laboratory, hospital-based, cross sectional study. Place and Duration of Study: Hematology clinic at Fedail hospital Khartou...
Open access
Research Article10.9734/JCTI/2016/29678
Recently there has been a renewed interest on the signaling pathways and metabolic changes in cancer cells. It is well known that there are several oncogenes and tumor suppressors that affect cancer metabolism and re-engineer it for better growth and survival. The best descriptio...
Open access
Research Article10.9734/JCTI/2016/29641
Objective: To study the incidence of nodal metastasis in early stage operable cases of cancer cervix and to correlate the nodal metastasis with different parameters like stage, degree of differentiation, lympho-vascular space invasion (LVSI) and deep stromal invasion. Materials...
Open access
Research Article10.9734/JCTI/2016/29494
Accurate diagnosis and proper monitoring of cancer patients remain important obstacles for successful cancer treatment. The search for cancer biomarkers is carried out in order to quickly identify tumor cells and predict treatment response, ultimately leading to a favorable thera...
Open access
Research Article10.9734/JCTI/2016/28234
Aim: Non-Hodgkin's primary lymphoma of the breast is rare. These tumors represent 0.04 to 0.52% of malignant breast pathology, 2.2% of extranodal lymphoma and 0.4% of all non-Hodgkin’s lymphoma. Clinical and radiological aspects show no special characteristics. The aim of our stu...
Open access
Research Article10.9734/JCTI/2016/28910
Secondary spread of cancer to bones is commonest and frequent phenomenon and enhances the need of special care for sufferers. Bone metastases mostly are the first complication of different variety of cancers which increase the need of care and expensive facilities. Blood dissemin...
Open access
Research Article10.9734/JCTI/2016/28440
Alkaline Phosphatase (s-ALP) has been extensively used to monitor the disease and screen the patients for cancer metastasis. Both the baseline s-ALP and changes in s-ALP have been reported as prognostic factors for treatment effect and survival in bony and liver metastatic breast...
Open access
Research Article10.9734/JCTI/2016/26755
Background: Childhood malignant tumors are among diseases that cause death to children below 14 years. Although it is the second most common cause of death in children in developed countries, its magnitude in Africa is not well known. Aim: To determine the proportion of pediatric...
Open access
Research Article10.9734/JCTI/2016/29031
Background: Recently we reported the successful in vitro cultivation of prostatic epithelial and stromal cells from patients with benign prostatic hyperplasia and adenocarcinoma of the prostate by liquid biopsy. In that study we noticed monocytes that were colonized by prostatic...
Open access
Research Article10.9734/JCTI/2016/28227