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Journal of Pharmaceutical Research International

· ISSN (electronic) 2456-9119

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175

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0

2026 articles

175

Open access

304

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Articles (175)

Formulation and Characterization of Dill Seed Vaginal Cream Based on a Traditional Medicine

Zohreh Sarhadinejad, Fariba Sharififar, Zarrin Sarhadynejad, Zohreh Salari, Haleh Tajadini, Farzaneh Mohamadi, Amir Asadi-Khanouki & Mehdi Ansari · Journal of Pharmaceutical Research International · 2018

Background: Dill seed has been used as a vaginal discharge remedy according to traditional origins, but its application by traditional methods is difficult and time-consuming. Aims: The main aim of this study was preparing a vaginal dosage form with acceptable physicochemical pro...

Open access Research Article 10.9734/JPRI/2018/42143

Rheological Properties of Low-calorie Red Deer Meat Pâté

Eleonora Okuskhanova, Maksim Rebezov, Zhanibek Yessimbekov, Diana Tazeddinova, Pavel Shcherbakov, Tatiana Bezhinar, Oksana Vagapova, Tatiana Shcherbakova & Marilyne Stuart · Journal of Pharmaceutical Research International · 2018

Background: The formulation of new meat products requires evaluation of the effect of different ingredients on physical-chemical and rheological properties of meat batters. Objective: In this study, the yield stress properties of three low-calorie meat pâté recipes were evaluated...

Open access Research Article 10.9734/JPRI/2018/42317

Upper Gastrointestinal Bleeding in the Absence of Proper pH Control in Patients Admitted to ICU

Afshin Zarghi, Fanak Fahimi & Behnaz Arabpanahan · Journal of Pharmaceutical Research International · 2018

Introduction: Stress-related mucosal disease (SRMD) occurs in many critically ill patients in Intensive Care Units (ICU) and may develop within 24 hours of admission. Proton pump inhibitors (PPI) therapy has been documented to produce more potent inhibition of gastric acid secret...

Open access Research Article 10.9734/JPRI/2018/39316

A Novel HPLC Method for Determination of Phenytoin in Human Plasma

Jesse Flores, Sheril Alexander & Mariana Babayeva · Journal of Pharmaceutical Research International · 2018

Aim: Aim of this research was to develop and validate a simple, efficient and reproducible high-performance liquid chromatography method to measure phenytoin concentrations in human plasma Study Design: Linearity, selectivity, sensitivity, accuracy and precision of the analytical...

Open access Research Article 10.9734/JPRI/2018/41885

Phytochemical Screening and Anti-Inflammatory Properties of the Hydroethanolic Leaf Extract of Calotropis procera (Ait). R. Br. (Apocynaceae)

Ernest Obese, Elvis Ofori Ameyaw, Robert Peter Biney, Isaac Tabiri Henneh, Fred Jonathan Edzeamey & Eric Woode · Journal of Pharmaceutical Research International · 2018

Aims: Inflammation has been implicated in many disorders and currently available therapies elicit adverse effects. The coarse shrub of Calotropis procera has been used in folk medicine to treat several ailments such as asthma, rheumatism and also fever. The anti-inflammatory pote...

Open access Research Article 10.9734/JPRI/2018/42529

Effects of Methanolic Extract of Vernonia amygdalina on Electrolytes and Renal Biomarkers in NaCl – Induced Hypertensive Male Wistar Rats

O. B. Onyema-iloh, S. C. Meludu, E. O. Iloh, C. E.Dioka . & C. N. Obi-Ezeani · Journal of Pharmaceutical Research International · 2018

Vernonia amygdalina popularly called bitter leaf is used in traditional medicine to treat fever, malaria, diarrhoea, dysentery and diabetes. They serve as laxatives and fertility inducer. They are commonly used as vegetable. The effects of methanolic extract of Vernonia amygdalin...

Open access Research Article 10.9734/JPRI/2018/41908

Antipsychotic Effects of Ethanol Leaf Extract and Fractions of Milicia excelsa (Moraceae) in Mice

Lateef Abiola Akinpelu, Moses Atanda Akanmu & Efere Martins Obuotor · Journal of Pharmaceutical Research International · 2018

Aim: This study investigated the acute toxicity (LD50) and antipsychotic potentials of ethanol leaf extract of Milicia excelsa (EME), hexane (HF), ethyl acetate (EAF), butanol (BF) and aqueous (AF) fractions in mice. Study Design: This study used experimental mice models predicti...

Open access Research Article 10.9734/JPRI/2018/42383

An In-vitro Antioxidant and Antidiabetic Evaluation of Traditional Medicinal Plants of Botswana

Mmopi N. Keneilwe, George Saramma & Chabaesele Kelvin · Journal of Pharmaceutical Research International · 2018

The present study was aimed at the in-vitro analysis of the antioxidant and antidiabetic potential of the methanol extracts of four perennial plants which are indigenous to Botswana and further to investigate whether their antihyperglycemic effects are working through the antioxi...

Open access Research Article 10.9734/JPRI/2018/42218

Exploring the Effect of Caffeine on Decelerating the Lethargic Action of Diclofenac in the Treatment of Pain

Mst. Marium Begum, Rubel Hossain, Md. Sahab Uddin, Md. Sohanur Rahman, Md. Motiar Rahman, Rita Saha, Asma Tabassum & Rubaba Karim · Journal of Pharmaceutical Research International · 2018

Background: Diclofenac is used as a potential analgesic for mild to moderately severe pain including migraine pain. However, the common side effect of this drug (drowsiness) becomes bothersome for patients taking diclofenac on regular basis in order to get rid of migraine pain. T...

Open access Research Article 10.9734/JPRI/2018/40988

Formulation and Evaluation of Metoprolol Tartrate Loaded Niosomes Using 23 Factorial Design

Sharmin Nahar, S. M. Ashraful Islam, Swarnali Islam Khandaker, Waheeda Nasreen, Ohinul Hoque & Irin Dewan · Journal of Pharmaceutical Research International · 2018

The purpose of this study was to formulate and evaluate metoprolol tartrate (MT) loaded liposomes using factorial design. Preparation of niosomal drug delivery of MT increased its bioavailability which led to being better therapeutic effects, reduced the frequency of dosing and d...

Open access Research Article 10.9734/JPRI/2018/42068