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Journal of Pharmaceutical Research International

· ISSN (electronic) 2456-9119

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175

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0

2026 articles

175

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304

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Articles (175)

Stem Bark Extract of Sterculia setig­era Delile Exhibits Anti-inflammatory Properties through Membrane Stabilization, Inhibition of Protein Denaturation and Prostaglandin E2 Activity

Isaac Tabiri Henneh, Robertson Akrofi, Elvis Ofori Ameyaw, Daniels Konja, George Owusu, Bashiru Abane, Joseph Acquah-Mills, Fred Jonathan Edzeameh & Francis Tayman · Journal of Pharmaceutical Research International · 2018

Aims: The stem bark of Sterculia setigera has been used in several African countries for the treatment of many inflammatory conditions. However, there is no scientific report to authenticate this usage. The current study, therefore, aims at assessing the in vitro and in vivo anti...

Open access Research Article 10.9734/JPRI/2018/42030

A Study of Ginseng Effects on Spermatogenesis Multiplications (TDI, RI, SI) Proceeding Scrotal Heat Shock Induction in Rat

Hamed Moradpour, Mehrdad Neshat & Esmaeil Safavi · Journal of Pharmaceutical Research International · 2018

Objective: Ginseng is a plant which has high Antioxidant feature and contains Ginsenosides that has a high affectivity on testicle’s tissue. This study is done to increase the survival of germ cells and also to find out its effects on decreasing the restoration time of damaged te...

Open access Research Article 10.9734/JPRI/2018/42177

Antihyperglycemic Activity of Swertia chirata on nSTZ-T2DM Rats: A Chronic Study

Amrita Bhowmik, M. Mosihuzzaman, Yearul Kabir & Begum Rokeya · Journal of Pharmaceutical Research International · 2018

Aim: The present study aimed to investigate antidiabetic effects and to explore the underlying mechanism of S. chirata on neonatal-streptozotocin induced type 2 diabetic model (nSTZ-T2DM) rats. Methodology: Stem-barks were collected from local market, identified from Bangladesh N...

Open access Research Article 10.9734/JPRI/2018/41878

Major Adverse Effects Associated with Tacrolimus (Fk506) Based Regimen among Saudi Kidney Transplant Patients

Ahmed S. Ali, Marzog S. Al-Nasser, Mai A. Abdul Sattar, Huda M. Alkreathy, Mohammed N. Al-Amma, Rayan A. Alsulaimani & Ezz H. Abdulfattah · Journal of Pharmaceutical Research International · 2018

Tacrolimus (Fk506)- based immunosuppressant regimen has become the cornerstone in managing kidney transplant patients (KTP) , where it has been used typically used on chronic basis. However, various adverse effects on multiple organ systems are expected and their incidence is dep...

Open access Research Article 10.9734/JPRI/2018/41611

Comparative Assessment of the Quality and Interchangeability of Some Brands of Dihydroartemisinin/Piperaquine Tablets Marketed in Niger Delta Region of Nigeria

M. Bagbi Baribefe, E. Omotoso Abayomi & I. Ukanireh Mkpongke · Journal of Pharmaceutical Research International · 2018

The research work was carried out to ascertain the quality and suitability for substitution in clinical practice of some brands of Dihydroartemisinin/Piperaquine phosphate (40 mg/320 mg) tablets marketed in Niger Delta Region of Nigeria. Ten different brands (A to J) of the drug...

Open access Research Article 10.9734/JPRI/2018/40186

Nutritive Value of Goat and Cow Milk Sampled from the Region of East Kazakhstan

Ainur Serikova, Sergazy Duyssembayev, Almagul Nurgazezova, Gulnur Nurymkhan, Salima Tugambayeva, Nurgul Ikimbayeva, Aizhan Akhmetzhanova, Eleonora Okuskhanova & Zhanibek Yessimbekov · Journal of Pharmaceutical Research International · 2018

This paper presents the results of a nutritional profile of goat’s milk sampled from the region of East Kazakhstan. The chemical composition determined showed that goat’s milk contained 4.63% fat, 3.5% protein and 8.14% non-fat milk solids, while cow’s milk had less fat (4.15%),...

Open access Research Article 10.9734/JPRI/2018/41889

Octanol-water Partition Coefficients Determination and QSPR Study of Some 3-hydroxy Pyridine-4-one Derivatives

R. Sabet, A. Fassihi & L. Saghaie · Journal of Pharmaceutical Research International · 2018

The partition coefficients (Kpart, in octanol/water system) of a range of bidentate ligands containing the 3-hydroxy pyridine-4-one moiety were determined using shake flask. These derivatives were subjected to quantitative structure-property relationships (QSPR) analysis. A colle...

Open access Research Article 10.9734/JPRI/2018/41142

Investigation of Hepatoprotective Properties of the Ethanolic Extract of Careya arborea Roxb. Bark in Paracetamol Induced Hepatotoxicity in Rats

Md. Rajibul Islam, Md. Jahir Alam, Md. Abdus Sobhan Khan & Kazi Mohsenatun Nessa Douti · Journal of Pharmaceutical Research International · 2018

Traditional plants have been utilized to manage hepatotoxicity according to recent trends. Careya arborea (CA) has been used in folk medicine to alleviate several diseases. In the present study, ethanolic extract of Careya arborea bark has been utilized to study its efficacy on p...

Open access Research Article 10.9734/JPRI/2018/41949

Evaluation of Triglyceride to High-Density Lipoprotein Cholesterol Ratio and Atherogenic Indices in Gestational Diabetes Mellitus

Maryam Jameshorani, Alireza Arefzadeh, Pooyan Khalighinejad, Sadegh Ranjbar & Saeideh Mazloomzadeh · Journal of Pharmaceutical Research International · 2018

Introduction: Gestational diabetes mellitus (GDM) is a common complication in pregnancy. Triglyceride (TG) to high-density-lipoprotein-cholesterol (HDL-c) ratio is an indicator of insulin resistance. Methods: Controversial findings of recent studies suggest that ethnicity and oth...

Open access Research Article 10.9734/JPRI/2018/41490