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Research Article Open access CC BY 4.0

Development and Validation of Novel Analytical Method for the Determination of Particle Size Distribution in Ciprofloxacin Hydrochloride Using Laser-based Particle Size Analyzer

Amit Gosar, Chetana Parange, Suyog Narvankar, Shivaji Jadhav, Vikram Patil

Journal of Advances in Medical and Pharmaceutical Sciences · pp. 40–47 · Published 27 Aug 2022

10.9734/jamps/2022/v24i730316

Abstract

This paper described a rugged and precise particle size determination method that has been developed and validated for the determination of particle size distribution of Ciprofloxacin Hydrochloride by a dry method using Malvern Mastersizer 2000. The Method of the particle size distribution of Ciprofloxacin Hydrochloride was precisely developed and validated successfully. By using parameters like Precision, Intermediate precision, and Robustness the method was validated. All the particle size data has been compiled and found to be satisfactory, Hence the method is suitably used for the analysis of the Particle size analyzer of Ciprofloxacin Hydrochloride active pharmaceutical ingredients.

Ciprofloxacin hydrochloride method validation Particle Size Analyzer (PSA)

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