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Research Article Open access CC BY 3.0

Characterization of Bioactive Sesquiterpenes, Organic Acids and Their Derivatives from the Leaves of Psidium guajava Linn

Okenwa U. Igwe, T. Abii

International Research Journal of Pure and Applied Chemistry · pp. 456–467 · Published 16 Apr 2014

10.9734/IRJPAC/2014/8592

Abstract

The isopropanolic extract of the leaves of Psidium guajava Linn was analyzed by Gas chromatography-mass spectrometry (GC-MS). Fourteen different phytochemical compounds have been characterized, including 1, 3, 3-trimethyl-2-oxabicyclo [2.2.2] octane, (2.06%), 4, 11, 11-trimethyl-bicyclo [7.2.0] undec-4-ene (6.26%), (E,E,E)-2, 6, 6, 9-tetramethyl-1, 4, 8-cycloundecatriene (1.05%), eudesma-4(14),11-diene (5.07%), guaia-1(10), 11-diene (4.63%), 3, 7, 11-trimethyl-1,6,10-dodecatriene-3-ol(4.01%), 1,3-dimethyl-8-(1-methylethyl)-tricyclo [4.4.0.0(2,7)] dec-3-ene (1.66%), 1, 1, 4, 7-tetramethyl-decahydro-1H-cycloprop[e] azulen-4-ol (11.00%), hexadecanoic acid methyl ester (1.53%), 4, 4, 8-trimethyltricyclo [6.3.1.0(1,5)] dodecane-2, 9-diol (2.78%), L-(+)-ascorbic acid 2,6-dihexadecanoate (20.43%), 7-octadecenoic acid methyl ester (3.81%), 3, 7, 11, 15-tetramethyl-2-hexadecen-1-ol (2.24%) and 9-octadecenoic acid (33.47%). The presence of these bioactive compounds in the leaves of Psidium guajava Linn could be the reason behind its use for the treatment of diseases and infections in herbal medicine in Nigeria.  

GC-MS analysis Psidium guajava bioactive compounds herbal medicine

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