Prevalence, Circulation and Characterization of Multi-resistant Bacteria at Omar Bongo Ondimba Army Instruction Hospital in Libreville

Abstract

Multi-resistant bacteria (MRB) pose a global health problem. They lead to increased morbidity, mortality and hospital costs. The main objective of this study is to study the prevalence, circulation and characterization of multi-resistant bacteria. This is a prospective cross-sectional study of 4 examinations. Bacterial identification was performed using Gram stains, oxidase, catalase, filamentation tests and the Api 20 STAPH, Api 20E systems. The assessment of sensitivity to antibiotics is based on the liquid diffusion method and on the ATB G, ATBTM-EU and ATBTM STAPH galleries previously soaked in antibiotics. The most common multidrug resistant bacteria were Klebsiella pneumonia, Escherichia coli, Enterobacter cloacae, MRSA and Acinetobacter baumanii. The number of multi-resistant bacteria from cytobacteriological urine examinations was 17, or 43.59% of all isolates. The prevalence of multi-resistant bacteria was 57.14% in blood cultures. In the collection of material from the hospital, the prevalence of multi-resistant strains was 72.73%. The prevalence of multi-resistant strains was 40% in the pus samples. These results can help define the research perspectives and strategies to be developed to better control the emergence and spread of multi-resistant bacteria in the hospital environment.