Sero-Surveillance and Risk Factors of Hepatitis B Virus among Pregnant Women in Sokoto, North-Western Nigeria
Alkali Bello Rabiu, Ottah Chidinma May, Shuaibu Abdulmalik Bello, Abubakar Firdausi Ibrahim, Audu Musa, Aisha Bello, Bello Mukhtar
International STD Research & Reviews · pp. 1–9 · Published 4 Apr 2018
10.9734/ISRR/2018/38992Abstract
Background: Maternal infection with Hepatitis B virus (HBV) can lead to chronic infection in the neonate, and the risk depends on her status of Hepatitis B surface antigen (HBsAg) and Hepatitis B e antigen (HBeAg). This study aimed at determining the sero-surveillance of HBV among pregnant women in Sokoto, Nigeria. Blood samples from 93 pregnant women were tested for the HBV using Immunochromatographic Methods (Aria, USA) and seropositive samples evaluated for TNF-alpha and ALT. Questionnaires were administered to get socio-demographic information. Statistical Analysis: SPSS ® statistical software. Results: The HBV seroprevalence was17.2% for HBsAg. Conclusions: The seroprevalence of HBsAg was 17.2%. Elevated TNF-alpha level and ALT level were associated with HBV infection. Therefore, screening of pregnant women for Hepatitis B is necessary to identify the neonates at risk.
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