Epithelioid Hemangioendothelioma of the Liver: A Case Report
F. Z. EL-Rhaoussi, S. M. Daoud, M. Tahiri, F. Haddad, W. Hliwa, A. Bellabah, Nisrine Bennani Guebessi, Siham Nagib, W. Badre
Asian Journal of Research and Reports in Hepatology · pp. 26–33 · Published 15 May 2023
Abstract
Epithelioid hemangioendothelioma of the liver (EHE) is a rare primary solid tumor of vascular origin [1-4]. EHE represents about 0.4% of all sarcomas and only 20% develop in the liver [5]. It occurs in a non-cirrhotic liver and its pathogenesis remains unknown. The involvement is often multinodular and may mimic metastases of a primary extrahepatic lesion and may delay the diagnosis. The clinical and biological signs are non-specific. Anatomopathological diagnosis can be difficult, requiring the precious help of immunohistochemistry. We report the clinical case of a 22-year-old patient admitted with febrile right hypochondrial pain, peritoneal and pleural effusion syndrome with a severe alteration of general condition. The diagnosis of hepatic EHE was proven on immunohistochemical study of the liver biopsy. The evolution was marked by the death of the patient.
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