Crude Flavonoids Isolated from the Stem Bark of Annona senegalensis have Antimicrobial Activity
Mahmoud Suleiman Jada, Wurochekke Abdullahi Usman, Ajayi Opeyemi Olabisi
Journal of Advances in Biology & Biotechnology · pp. 24–29 · Published 10 Oct 2014
10.9734/JABB/2015/11884Abstract
This study was aimed at determining the in vitro antimicrobial activity of crude flavonoids isolated from the stem bark of Annona senegalensis. The study was carried out in the laboratory of Biochemistry department, Modibbo Adama University of Technology, Yola, Adamawa State, Nigeria, between July and October, 2013. The antimicrobial activity was carried out using agar well diffusion method. Phytochemical screening of the methanolic stem bark extract of Annona senegalensis revealed the presence of steroids, saponins, anthraquinones, flavonoids, tannins and cardiac glycosides. Crude flavonoid of 1.956g was found to be present in 10g of stem-bark extract of the plant. Streptomycin was used as standard which gave the zones of inhibition of 23mm against Escherichia coli, 26mm against Salmonella typhi and 28mm against Shigella specie while the isolated crude flavonoids from the stem bark of Annona senegalensis gave the zones of inhibition of 18mm against Escherichia coli, 25 mm against Salmonella typhi and 26 mm against Shigella specie. Crude flavonoids exhibited Minimum Inhibitory Concentration (MIC) against Shigella specie and Escherichia coli at 100mg/ml while against Salmonella typhi at 50mg/ml. In conclusion, the crude flavonoids isolated from the stem bark of Annona senegalensis have antimicrobial activity against the test organisms.
Cited by 8
G'massampou Datagni, Aklesso Pouwelong Mouzou, Kossi Metowogo · Journal of Drug Delivery and Therapeutics · 2021
Moshood Abiola Folawiyo, Idowu Olamiposi Omotuyi, Folashade Omobolanle Ajao · Applied Biochemistry and Biotechnology · 2023
Omolara F. Yakubu, Damilohun S. Metibemu, Isaacson B. Adelani · Biomedicine & Pharmacotherapy · 2020
A.M. Baldé, M.S. Traoré, M.A. Baldé · Journal of Ethnopharmacology · 2016
Omale Aminu, Ekere Nwachukwu Romanus, Omale Jamila Audu · Current Analytical Chemistry · 2025
Matthew C. Achilonu, Xolile V. Ngubane, S'busiso M. Nkosi · South African Journal of Science · 2023
Rahmat Adetutu Adisa, Naimat Kolawole, Lateef A. Sulaimon · Toxicological Research · 2019
Yilave, B. M., Sar, T. T., Agada, E. O. · UMYU Journal of Microbiology Research (UJMR) · 2024
Related research
- Nutrient Analysis and Antimicrobial Activities of the Leaves and Fruit Pulp Extracts of Tetrapluera tetraptera on Clinical Bacteria Isolates — shares topic coverage
- Antibacterial and Phytochemical Activity of Gliricidia sepium against Poultry Pathogens — shares topic coverage
- Antibacterial Screening of Two Indigenous Nigerian Spices; Piper guineense and Xylopia aethiopica — shares topic coverage
- In vitro Antibacterial Activity of the Extracts of Peperomia pellucida (L) — shares topic coverage
- Phytochemical and Antibacterial Investigation of Leaf Extracts of Vernonia amygdalina — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
8
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.