Antibacterial and Biofilm Inhibition Activities of Nicotiana tabacum Extracts against Streptococcus mutans Isolated from the Oral Cavity
Microbiology Research Journal International · pp. 1–6 · Published 23 Apr 2020
10.9734/mrji/2020/v30i330199Abstract
Aim: To determine the antibacterial activity and biofilm inhibitory activity of Nicotiana tabacum leaf extract against Streptococcus mutans isolated from oral cavity. Place and Duration of Study: Department of Microbiology, Faculty of Science, Imo State University, Owerri, Nigeria, between April and November 2019. Methodology: The study was carried out using the agar diffusion method for antibacterial activity and microtiter assay method for the biofilm inhibition effect. Results: All four extracts of hot water, ethanol, acetone and methanol tested against S. mutans had no antibacterial activity as no zone of inhibition was recorded. Likewise, all the extracts did not inhibit the formation of biofilm by the organism on glass. This is seen in the increase of the optical density (OD) values from 0.572 to 0.804 for water, 0.260 to 1.420 for ethanol, 0.216 to 0.626 for acetone and 0.236 to 0.725 for methanol extracts respectively. Conclusion: This study therefore indicates that N. tabacum does not have antibacterial and biofilm inhibitory against S. mutans. This also explains why a lot of tobacco users still suffer from dental caries and other oral infections caused by S. mutans.
Cited by 0
No indexed citations yet.
Related research
- Odontogenic Keratocyst: A Case Series — shares topic coverage
- Fibrolipoma of Oral Cavity- A Case Study — shares topic coverage
- Assessing Salivary Flow Rate, Salivary pH and Oral Candidiasis among Tobacco Chewers, Smokers and Healthy Controls- A Cross Sectional Study — shares topic coverage
- Effects of Tobacco Cigarette Smoking on Some Hematological Parameters of Male Cigarette Smokers in Southern Nigeria — shares topic coverage
- Antibacterial Activities of Streptomyces collinus and Streptomyces refuineus from Cocoa, Orange and Timber Plantation Soils in Akure Metropolis — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
0
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.