Antibiogram of Wound Isolates of Patients Attending University of Port Harcourt Teaching Hospital, Nigeria

Abstract

The risk of wound infection increases with the degree of contamination and it has been estimated that about 50% of wounds contaminated with bacteria become clinically infected. Profile of bacteria isolated from wound infections in patients attending University of Port Harcourt teaching Hospital (UPTH) were investigated. One hundred and eight wound isolates were collected from male and female patients and cultured on nutrient agar, MacConkey and blood agar. Based on morphological and biochemical characteristics of the isolates, Staphylococcus aureus 44(40.75%) was the most prevalent in wound infection in the study area in both male and females followed by Pseudomonas aeruginosa 28(25.9%), Klebsiella spp. 14(13.0%), Proteus spp. 10(9.3%) and Escherichia coli 12(11.1%). The antibiogram showed the presence of multi-drug resistant organisms. The percentage susceptibility of the isolates was: Imipenem (80%), Gentamycin (62%) clindamycin (30%), and levofloxacin (30%). Thus, these antibiotics should be considered as first line drug in the treatment of wound in the area as they were the most effective antibiotics. Prompt and timely treatment is therefore, recommended on the onset of wound infections.