Synthesis, Characterization, Swiss ADME and Antimicrobial Activity of Copper (II) Complex with 2-Sulfanilamidopyrimidine: Through DFT Spectroscopic with Profound Biological Implications
Mohd. Washid Khan, Ravi Prakash Mishra, Bhavesh Patel, Shradha Patel, Sujit Gupta, Souvik Sen
Asian Journal of Applied Chemistry Research · pp. 16–32 · Published 21 Jul 2021
10.9734/ajacr/2021/v9i130203Abstract
Sulphadiazine and their copper metal complexes are dexterous ligands, which are condensation products of primary amines with carbonyl compounds gaining importance day by day in the present scenario. Spectral characterization and examination of the potential antimicrobial and antioxidant activity of the synthesized complex were performed. The imine Cu(II) complex is characterized by FTIR and UV/Vis spectroscopy. The Stoichiometric M:L ratio was determined by Joe and Jones method. These compounds and their copper metal complex are very important in various biological systems and their medicinal and pharmaceutical fields. Schiff foundations show beneficial natural functions such as anti-inflammatory, analgesic, antimicrobial, anticonvulsant, antitubercular, anticancer, antioxidant, anthelmintic, and antiglycation. The present review summarizes information on the diverse biological activities and also highlights the recently synthesized numerous Schiff bases and their metal complex as potential bioactive core.
Cited by 6
Mustafa Bal, Ayşegül Köse · Journal of Photochemistry and Photobiology A: Chemistry · 2024
Rimsha Qurrat-ul-ain, Mehboob Ur Rahman, Hafiz Muhammad Javed · Inorganic Chemistry Communications · 2024
Binesh Kumar, Daksh Khurana, Jai Devi · Inorganic Chemistry Communications · 2024
Taha Yasin BAYRAM, Merve YILDIRIM, Elif AKSAKAL · 2025
Elif Şenkuytu, Derya Davarcı, Seda Mesci · Journal of Molecular Structure · 2024
Showing 5 of 6 known citations — external sources report more than can currently be individually listed.
Related research
- Saponin: Properties, Methods of Evaluation and Applications — shares topic coverage
- Pharmacological and Therapeutic Activities of Kigelia africana (Lam.) Benth — shares topic coverage
- Facile Preparation of a Nanostructured Silver Oxide from a Mixed Ligand Coordination Polymer: Characterization and Biological Activity — shares topic coverage
- QSAR Study of Series of HEPT (1-[(2-hydroxyethoxy) methyl]-6-(phenylthio)thyio)thymine) Derivatives Using Genetic Function Approximation as Anti-HIV-1 Agents — shares topic coverage
- Determination of Total Protein, Superoxide Dismutase, Catalase Activity and Lipid Peroxidation in Soil Macro-fauna (Earthworm) from Onitsha Municipal Open Waste Dump — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
6
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.