Bio-active Compounds (Curcumin, Allicin and Gingerol) of Common Spices used in Indian and South-east Asian Countries Might Protect against COVID-19 Infection: A Short Review
Jawed Alam, Tahziba Hussain, Sanghamitra Pati
European Journal of Medicinal Plants · pp. 65–78 · Published 31 Dec 2020
10.9734/ejmp/2020/v31i2030363Abstract
Presently, our world is suffering with COVID-19 caused by novel coronavirus SARS- CoV-2. The high rate of mutation in SARS- CoV-2 helps viruses to become resistance against pre-existent anti-viral medications. Currently, there are no effective therapeutic strategies against COVID-19 infection except some vaccines. Curcumin, Allicin and Gingerol are natural bioactive compounds having anti-viral, anti-inflamatory, anti-pyretic, anti-fibrotic properties and were used as spices in food in South East Asian and Indian subcontinent that could be a potential treatment for COVID-19 disease. This review will help in understanding the biology and potential of bioactive compounds present in turmeric, garlic and ginger as therapeutic against COVID-19 infection. Computational study suggested that gingerol, curcumin, and allicin showed good interaction with proteins of SARS-CoV-2 and ACE2 receptor of host cell and might have an important role in impeding SARS-CoV-2 replication. Clinical trials have been conducted for nanocurcumin and gingerol. The fatality rate of people from South East Asia and Indian subcontinent eating highly spicy food is less as compared to people from America and Europe eating less spicy food. Further, this review will help people to do research on curcumin, allicin and gingerol against the treatment of COVID-19. All of the spices are commercially available, edible and might be used as precautionary home remedies against COVID-19.
Cited by 7
7 citations reported by external sources — individual citing-article records aren't available to list yet.
Related research
- Covid-2019:“A Microbiological Monster” — shares topic coverage
- COVID 19 Disease Caused by Coronavirus 2 (SARS-CoV-2) (Severe Acute Respiratory Syndrome) — shares topic coverage
- Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2): What Can Africa Learn from Ongoing Research in Epidemiology, Clinical Manifestations, Chemotherapy and Prevention? — shares topic coverage
- Azithromycin and Hydroxychloroquine Accelerate Recovery of Outpatients with Mild/Moderate COVID-19 — shares topic coverage
- Early Treatment with Hydroxychloroquine Improves Clinical Outcomes and Reduces Hospital Admissions in COVID-19 Associated Pneumonia — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
7
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.