Rare Presentation of Aggressive B-Cell Lymphoma as Ileocolic Intussusception in a Young Adult: A Case Report

Abstract

Intussusception is defined as the telescoping of a segment of the gastrointestinal tract into an adjacent one. Adult intussusception, a rare yet critical gastrointestinal occurrence, accounts for 5% of all intussusceptions. Primary gastro-intestinal lymphoma accounts for 1–4% of all gastro-intestinal malignancies. 90% of them have B-cell non-Hodgkin lymphoma (NHL). The most prevalent lymphoma producing intussusception is diffuse large B-cell lymphoma. We report a case of a 21-year-old male with acute ileocolic intussusception who was ultimately diagnosed with aggressive B-cell lymphoma. Computed tomography showed ileo-colic intussusception. A right hemicolectomy was performed, with ileotransverse anastomosis  was done with post-operative chemotherapy. This case illustrates the rare occurrence of intussusception secondary to lymphoma in adults. We emphasize the importance of including diffuse large B-cell lymphoma in the differential diagnosis of adult ileocolic intussusception to ensure accurate diagnosis and appropriate management.