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Research Article Open access CC BY 4.0

Evaluating the Therapeutic Efficacy of L-Lysine Aescinat Supplementation on Neurological Outcomes in Patients with Spinal Fractures and Traumatic Spine Injuries: A Prospective Cohort Study from Tbilisi, Georgia

Koka Gogichashvili, Zviad Malazonia, Tornike Kldiashvili, Ciara Francesca Maxwell

Journal of Advances in Medical and Pharmaceutical Sciences · pp. 6–13 · Published 20 Feb 2024

10.9734/jamps/2024/v26i4678

Abstract

This prospective study aimed to comprehensively investigate the impact of L-Lysine aescinat supplementation on the neurological outcomes of patients recovering from spinal fractures and traumatic spine injuries. A total of 32 patients were recruited and categorised into two groups: Group A (n=16), receiving L-Lysine aescinat supplementation, and Group B (N=16), serving as the control group without L-Lysine aescinat administration. The primary objective was to assess changes in the Karnofsky performance scale, a functional and well-being neurological assessment tool especially for those undergoing operations or with chronic illness, over a follow up period of one month in order to determine if L-Lysine aescinat had an immediate effect on recovery in the post-operative period. Urinary dysfunction was noted, alongside the location of the fracture, type of surgery and if there were any significant comorbidities.

Therapeutic efficacy L-Lysine supplementation neurological outcomes spinal fractures traumatic spine injuries

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