A Case Report of Fatal Colonic Perforation Due a Necrotizing Pancreatitis
Tijani Nissrine, El Bakuri Abdelilah, Ettaoussi Abdelhak, Majd Abdessamad, Kamal Khadija, Bouali Mounir, El hattabi Khalid
Asian Journal of Case Reports in Surgery · pp. 407–413 · Published 7 Jul 2025
10.9734/ajcrs/2025/v8i2657Abstract
Severe acute pancreatitis can lead to rare but potentially fatal complications, including colonic perforation. We report the case of a 38-year-old patient, with no previous medical history, admitted for colonic perforation following severe acute pancreatitis of gallstone origin, whose progression was marked by hemodynamic instability and, subsequent, intraoperative death. This serious complication (Werge et al., 2016) remains rare but should be considered in the face of a sudden deterioration in the clinical condition of a patient with necrotizing pancreatitis. Parietal ischemia secondary to local inflammation, vascular compression, and enzymatic necrosis phenomena may explain this perforation. Close monitoring and repeated imaging are essential for early diagnosis and appropriate surgical management.
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M. Anas, Imad Ali, Hazique Jameel · Journal of Surgical Case Reports · 2026
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