A Case Report on Reversible Toxic Optic Neuropathy on Long Term Treatment of Linezolid in Extensively Drug-Resistant Tuberculosis Patient

Sunil Kardani; Rajesh Hadia; Ashish Shah; Ghanshyam Parmar; Rajesh Maheshwari; Avinash Seth; Trupal Rathod; Dhaval Joshi

doi:10.9734/jpri/2021/v33i37A31972

Research Article Open access CC BY 4.0

A Case Report on Reversible Toxic Optic Neuropathy on Long Term Treatment of Linezolid in Extensively Drug-Resistant Tuberculosis Patient

Sunil Kardani, Rajesh Hadia, Ashish Shah, Ghanshyam Parmar, Rajesh Maheshwari, Avinash Seth, Trupal Rathod, Dhaval Joshi

Journal of Pharmaceutical Research International · pp. 7–11 · Published 13 Jul 2021

10.9734/jpri/2021/v33i37A31972

Abstract

We describe a case of Linezolid-induced severe toxic optic neuropathy in a patient with drug-resistant tuberculosis. Linezolid produced severe toxic optic neuropathy in some who used it for a long time. To the best of our knowledge, the optic neuropathy was completely reversed after omitting Linezolid which is one of the effective drug regimens in his prescription, with significant improvements in eye vision.

Extensive drug resistance tuberculosis drug-induced optic neuropathy linezolid induced severe toxic optic neuropathy

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Sunil Kardani, Rajesh Hadia, Ashish Shah, Ghanshyam Parmar, Rajesh Maheshwari, Avinash Seth, Trupal Rathod, Dhaval Joshi (2021). A Case Report on Reversible Toxic Optic Neuropathy on Long Term Treatment of Linezolid in Extensively Drug-Resistant Tuberculosis Patient. Journal of Pharmaceutical Research International , 7–11. https://doi.org/10.9734/jpri/2021/v33i37A31972

Affiliations

Sunil Kardani — Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Vadodara-391760, Gujarat, India.
Rajesh Hadia — Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Vadodara-391760, Gujarat, India.
Ashish Shah — Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Vadodara-391760, Gujarat, India.
Ghanshyam Parmar — Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Vadodara-391760, Gujarat, India.
Rajesh Maheshwari — Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Vadodara-391760, Gujarat, India.
Avinash Seth — Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University, Vadodara-391760, Gujarat, India.
Trupal Rathod — Department of Pharmacy Practice, Maliba Pharmacy College, Mahuva-Bardoli Road, Bardoli-394350, Gujarat, India.
Dhaval Joshi — Department of Pharmacy Practice, Maliba Pharmacy College, Mahuva-Bardoli Road, Bardoli-394350, Gujarat, India.

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