A Comparative Study of the Antifungal Activity of Fresh and Dried Solanum anguivi Fruits on Candida albicans  and Trichophyton rubrum

Ouattara Sitapha; Kporou Kouassi Elisée; KRA Adou Koffi Mathieu; Appia Franck Hermann Desire; Yapo Adou Francis; N’guessan Jean David; Djaman Allico Joseph

doi:10.9734/ejmp/2024/v35i11176

Research Article Open access CC BY 4.0

A Comparative Study of the Antifungal Activity of Fresh and Dried Solanum anguivi Fruits on Candida albicans and Trichophyton rubrum

Ouattara Sitapha, Kporou Kouassi Elisée, KRA Adou Koffi Mathieu, Appia Franck Hermann Desire, Yapo Adou Francis, N’guessan Jean David, Djaman Allico Joseph

European Journal of Medicinal Plants · pp. 26–34 · Published 2 Mar 2024

10.9734/ejmp/2024/v35i11176

Abstract

In Côte d'Ivoire, as elsewhere in Africa, Solanum anguivi Lam is widely used in traditional medicine to treat bacterial and fungal infections. Given the importance of this plant, the extracts 70%, 80% and 100% from fresh and dried fruits was evaluated for the in vitro growth of two isolates of pathogenic fungi (Candida albicans and Trichophyton rubrum), as well as its anti-free radical activity. Antifungal tests were carried out by plating 1000 cells of each isolate on Sabouraud agar medium using the double dilution method in inclined tubes. Both extracts were active on the different strains tested, according to a dose-response relationship based on the principle of the method used. However, extracts from fresh fruit showed good activity on C. albicans, while the dried fresh fruit extracts were highly active on T. rubrum.

Solanum anguivi Lam antifungal Candida albicans Trichophyton rubrum

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Ouattara Sitapha, Kporou Kouassi Elisée, KRA Adou Koffi Mathieu, Appia Franck Hermann Desire, Yapo Adou Francis, N’guessan Jean David, Djaman Allico Joseph (2024). A Comparative Study of the Antifungal Activity of Fresh and Dried Solanum anguivi Fruits on Candida albicans and Trichophyton rubrum. European Journal of Medicinal Plants , 26–34. https://doi.org/10.9734/ejmp/2024/v35i11176

Affiliations

Ouattara Sitapha — Biology and Health Laboratory, Felix Houphouet-Boigny University, Cocody, Abidjan, 22 BP 582 Abidjan 22, Côte d’Ivoire.
Kporou Kouassi Elisée — Department of Biochemistry and Microbiology, Research Unit of Bioactive Natural Substances, Jean Lorougnon Guede University, Daloa, BP 150 Daloa, Côte d’Ivoire.
KRA Adou Koffi Mathieu — Biology and Health Laboratory, Felix Houphouet-Boigny University, Cocody, Abidjan, 22 BP 582 Abidjan 22, Côte d’Ivoire.
Appia Franck Hermann Desire — Biology and Health Laboratory, Felix Houphouet-Boigny University, Cocody, Abidjan, 22 BP 582 Abidjan 22, Côte d’Ivoire.
Yapo Adou Francis — Biology and Health Laboratory, Felix Houphouet-Boigny University, Cocody, Abidjan, 22 BP 582 Abidjan 22, Côte d’Ivoire.
N’guessan Jean David — Biology and Health Laboratory, Felix Houphouet-Boigny University, Cocody, Abidjan, 22 BP 582 Abidjan 22, Côte d’Ivoire.
Djaman Allico Joseph — Biology and Health Laboratory, Felix Houphouet-Boigny University, Cocody, Abidjan, 22 BP 582 Abidjan 22, Côte d’Ivoire and Medical and fundamental Biochemistry, Pasteur Institute / Company, Cocody, Abidjan, 01 BP 490 Abidjan 01, Côte d’Ivoire.

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