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Research Article Open access CC BY 4.0

A Review on the Reported Antibacterial Activity of 1,3,5-Triazine

Mrinmoy Basak, Biplab Kumar Dey, Sajidul Hoque Ansari, Moksood Ahmed Laskar, Priyanka Goswami, Rosamund Jyrwa, Pal Gogoi, Md. Rejwan Ahmed Choudhury

Journal of Pharmaceutical Research International · pp. 279–292 · Published 8 Nov 2021

10.9734/jpri/2021/v33i48A33251

Abstract

Antibiotics are the class of drugs used for bacterial, viral & fungal infection. Antibiotic resistance is the ability of microorganism to withstand themselves against the effects of a drug. Every year antibiotic resistance causes more than 38000 deaths in Thailand, 23000 deaths in USA. In South Asia one new born child dies every 5 minutes from blood stream infection because antibiotics given are ineffective due to bacterial resistance. Now antibiotic resistance is a threat to global health. In this paper, triazene derivatives are kept in concern.  Triazines are six-membered, nitrogen-containing heterocyclic scaffold with a wide range of pharmaceutical properties such as antibacterial, antifungal, anticancer, antioxidants, antitubercular, antimalarial and anti-inflammatory. Due to lack of new antibiotics as well older antibiotic are rapidly proving ineffective, derivatives of triazine would be of great significance in future prospective.

Triazine antibacterial antifungal

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