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Research Article Open access CC BY 4.0

An Assessment of Azithromycin Prescribed Interactions’ at the Outpatient Setting

Nehad J. Ahmed, Altaf Ali Mangi, Menshawy A. Menshawy, Ziyad S. Almalki, Mohammed A. Alhajri

Journal of Pharmaceutical Research International · pp. 102–107 · Published 5 Nov 2020

10.9734/jpri/2020/v32i2630844

Abstract

Aims: The present study was designed to identify and assess the severity of azithromycin interactions with other drugs in the outpatient setting in Alkharj. Methodology: A retrospective analysis was performed of azithromycin prescriptions in the outpatient setting in a public hospital in Alkharj in order to determine the incidence of interactions between azithromycin and other medications. Results: There were 182 prescriptions included in the study. There was a major interaction in only 1 prescription (0.55%) and moderate interactions in 15.30% of the prescriptions. So the percentage of overall interactions was about 20.88%. The most common drug interactions in the present study were between azithromycin and salbutamol. Conclusion: It can be concluded that the interactions between azithromycin with other medications were common, but these interactions could lead to irregular heart rhythm and lead to muscle pain and weakness. Adoption of international standard and locally conformable guidelines of antibiotic use can help in avoiding such problems.

Azithromycin drug Interactions DDIs outpatient.

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