An Overview of the Epidemiology, Pathogenesis, Diagnosis, and Treatment of Human Parvovirus B19
Kumaran Vadivel, Balaji Nandagopal, Mageshbabu Ramamurthy, Nithiyanandan Saravanan, Prashanth Rajendiran
Asian Journal of Research in Infectious Diseases · pp. 32–43 · Published 1 Dec 2022
10.9734/ajrid/2022/v11i4226Abstract
Human Parvovirus B19 (HPV-B19) infections are reported from different parts of the globe. The infection occurs in all age groups; however, most infections occur in childhood. There is evidence of exposure to the virus in about 80% of adults when screened for specific IgG. HPV-B19 is incriminated in several conditions like erythema infectious, aplastic crisis, hydrops fetalis and arthropathy. HPV-B19 is a cause of the Fifth disease (erythema infectious); it could also cause a febrile illness with or without rash in adults. Many adults especially women develop arthropathy and the condition could be chronic following a febrile illness. Patients (adults) with End Stage Renal Disease (ESRD) are prone to develop aplastic crisis or chronic anemia [1]. This review article aims to comprehensively describe the etiology, epidemiology, clinical features, diagnostic methods, and treatment in the management of HPV-B19.
References (56)
- 1 Experimental Parvoviral Infection in Humans [DOI]
- 2 A Viral Phospholipase A2 Is Required for Parvovirus Infectivity [DOI]
- 3 Clinical aspects of parvovirus B19 infection [DOI]
- 4 Intravenous Immunoglobulin Therapy for Pure Red Cell Aplasia Related to Human Parvovirus B19 Infection: A Retrospective Study of 10 Patients and Review of the Literature [DOI]
- 5 Seroprevalence of parvovirus B19 in the German population [DOI]
- 6 HUMAN PARVOVIRUS ARTHROPATHY [DOI]
- 7 Pure Red-Cell Aplasia of 10 Years' Duration Due to Persistent Parvovirus B19 Infection and Its Cure with Immunoglobulin Therapy [DOI]
- 8 Clinical Manifestations of Human Parvovirus B19 in Adults [DOI]
- 9 The Role of Parvovirus B19 in Aplastic Crisis and Erythema Infectiosum (Fifth Disease) [DOI]
- 10 The VP1 Unique Region of Parvovirus B19 and Its Constituent Phospholipase A2-Like Activity [DOI]
- 11 Pathogenesis of human parvovirus B19 in rheumatic disease [DOI]
- 12 Human parvovirus infection in homozygous sickle cell disease [DOI]
- 13 Persistent B19 infection in immunocompetent individuals: implications for transfusion safety [DOI]
- 14 The age-specific prevalence of human parvovirus immunity in Victoria, Australia compared with other parts of the world [DOI]
- 15 The transfusion-associated transmission of parvovirus B19 [DOI]
- 16 Replication of B19 parvovirus in highly enriched hematopoietic progenitor cells from normal human bone marrow [DOI]
- 17 Slow Clearance of Human Parvovirus B19 Viremia following Acute Infection [DOI]
- 18 Identification and genetic diversity of two human parvovirus B19 genotype 3 subtypes [DOI]
- 19 Parvovirus B19-Induced Apoptosis of Hepatocytes [DOI]
- 20 Conformational Changes in the VP1-Unique Region of Native Human Parvovirus B19 Lead to Exposure of Internal Sequences That Play a Role in Virus Neutralization and Infectivity [DOI]
- 21 Phylogenetic analysis of human parvovirus B19, indicating two subgroups of genotype 1 in Vietnamese patients [DOI]
- 22 The prevalence of human parvovirus B19 DNA and antibodies in blood donors from four Chinese blood centers [DOI]
- 23 Parvovirus B19 infection transmitted by transfusion of red blood cells confirmed by molecular analysis of linked donor and recipient samples [DOI]
- 24 Antiviral effect of cidofovir on parvovirus B19 replication [DOI]
- 25 Identification and characterization of acute infection with parvovirus B19 genotype 2 in immunocompromised patients in Poland [DOI]
- 26 Prevalence and genotypic characterization of human parvovirus B19 in children with hemato‐oncological disorders in North India [DOI]
- 27 Occupational Risk of Human Parvovirus B19 Infection for School and Day-care Personnel During an Outbreak of Erythema Infectiosum [DOI]
- 28 Identification of human parvovirus B19 infection in idiopathic nonimmune hydrops fetalis [DOI]
- 29 Human Parvovirus B19: Prevalence of Viral DNA in Volunteer Blood Donors and Clinical Outcomes of Transfusion Recipients [DOI]
- 30 Occupational Risk Factors for Infection with Parvovirus B19 among Pregnant Women [DOI]
- 31 Diagnosis and quantitative evaluation of parvovirus B19 infections by real‐time PCR in the clinical laboratory [DOI]
- 32 Haematological response to parvovirus B19 infection in homozygous sickle-cell disease [DOI]
- 33 Persistent parvovirus B19 infections in immunocompromised children [DOI]
- 34 Parvovirus B19 Infection Contributes to Severe Anemia in Young Children in Papua New Guinea [DOI]
- 35 Parvovirus B19 outbreak on an adult ward [DOI]
- 36 Cytokines in parvovirus b19 infection as an aid to understanding chronic fatigue syndrome [DOI]
- 37 Diagnosis and Management of Human Parvovirus B19 Infection [DOI]
- 38 Parvovirus B19V infection in Israel: prevalence and occurrence of acute infection between 2008 and 2013 [DOI]
- 39 Prevalence of human parvovirus (B19) and rubellavirus infections in urban and remote rural areas in northern Brazil [DOI]
- 40 Parvovirus B19 Infection in Hospital Workers: Community or Hospital Acquisition? [DOI]
- 41 Evaluation of serological assays for identification of parvovirus B19 immunoglobulin M [DOI]
- 42 Parvovirus B19 Infections and Blood Counts in Blood Donors [DOI]
- 43 Diagnosing human parvovirus B19 infection: Guidelines for test selection [DOI]
- 44 Nosocomial Exposure to Parvovirus B19: Low Risk of Transmission to Healthcare Workers [DOI]
- 45 Human parvovirus B19 infection in healthcare workers [DOI]
- 46 Seroprevalence of Antibodies to Parvovirus B19 among Children in Papua New Guinea [DOI]
- 47 PARVOVIRUS B19-ASSOCIATED TRANSIENT RED CELL APLASIA IN CHILDREN: The Role of Bone Marrow Examination in Unusual Presentations [DOI]
- 48 Prenatal Diagnosis of Parvovirus B19-Induced Hydrops Fetalis by Chemiluminescence In Situ Hybridization [DOI]
- 49 A Case of Persistent Parvovirus B19 Infection with Bilateral Cartilaginous and Ligamentous Damage to the Wrists [DOI]
- 50 Evidence of Serological Cross-Reactivity between Genotype 1 and Genotype 3 Erythrovirus Infections [DOI]
- 51 Parvovirus B19 [DOI]
- 52 Human Parvo Virus B19 Infection among Hospital Staff Members after Contact with Infected Patients [DOI]
- 53 The seroprevalence of parvovirus B19 infection in pregnant women in Sudan [DOI]
- 54 Infection and immunity for human parvovirus B19 in patients with febrile exanthema [DOI]
- 55 Hematologic manifestations and diagnosis of parvovirus B19 infections.
- 56 A nosocomial parvovirus B19 infection-induced transient aplastic crisis in a patient with chronic renal failure [DOI]
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