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Research Article Open access CC BY 4.0

An Overview of the Epidemiology, Pathogenesis, Diagnosis, and Treatment of Human Parvovirus B19

Kumaran Vadivel, Balaji Nandagopal, Mageshbabu Ramamurthy, Nithiyanandan Saravanan, Prashanth Rajendiran

Asian Journal of Research in Infectious Diseases · pp. 32–43 · Published 1 Dec 2022

10.9734/ajrid/2022/v11i4226

Abstract

Human Parvovirus B19 (HPV-B19) infections are reported from different parts of the globe. The infection occurs in all age groups; however, most infections occur in childhood. There is evidence of exposure to the virus in about 80% of adults when screened for specific IgG. HPV-B19 is incriminated in several conditions like erythema infectious, aplastic crisis, hydrops fetalis and arthropathy. HPV-B19 is a cause of the Fifth disease (erythema infectious); it could also cause a febrile illness with or without rash in adults. Many adults especially women develop arthropathy and the condition could be chronic following a febrile illness. Patients (adults) with End Stage Renal Disease (ESRD) are prone to develop aplastic crisis or chronic anemia [1].  This review article aims to comprehensively describe the etiology, epidemiology, clinical features, diagnostic methods, and treatment in the management of HPV-B19.

Arthropathy End-stage renal disease febrile illness IgM HPV-B19

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