Analysis of Atherogenic and Anthropometric Profiles of Normotensive and Hypertensive Ghanaians in the Kumasi Metropolis
Isaac K. Owusu, Christiana Aryee, William K. B. A. Owiredu, James Osei-Yeboah, Ellis Owusu-Dabo, Edwin F. Laing
Journal of Advances in Medicine and Medical Research · pp. 378–397 · Published 26 Feb 2015
10.9734/BJMMR/2015/14308Abstract
Ghana is undergoing a rapid epidemiological transition from solely communicable to a double burden of infectious and chronic disease such as hypertension. Aims: We aimed to compare the association between different lifestyle practices, adiposity indices, atherogenic dyslipidaemic parameters and hypertension as well as the prognostic implications for the levels of these parameters on target cardiac organ damage among hypertensives. We also determined the optimal threshold points and the discriminative power of these parameters on this urban Ghanaian hypertensive population. Study Design: A hospital-based case–control study was conducted. Methodology: The study purposively recruited 241 Ghanaian indigenes in the Kumasi metropolis, with 180 hypertensives as cases and 61 normotensives as controls. In addition to socio-demographic data captured, all participants underwent standard haemodynamic, anthropometric, atherogenic lipid and cardiac organ damage assessment. Results: In general, the case group presented with a significantly poorer atherogenic lipid profile compared to their counterparts in the control group. Participants presenting with significantly higher multiple atherogenic scores were found to cluster at the upper quartiles of systolic blood pressure, diastolic blood pressure and pulse rate. Population-specific threshold for waist circumference of >75 cm for females and >80 cm for male were the best adiposity indices for discriminating hypertension. Increasing atherogenic dyslipidaemia was more prevalent with the presence of cardiac target organ damage. Conclusion: In this urban population, higher altered lipid scores and abdominal obesity aggravated by lifestyle choices including alcohol consumption, smoking and physical inactivity may constitute significant risk for cardiovascular complications among hypertensives.
References (57)
- 1 Harmonizing the Metabolic Syndrome [DOI]
- 2 The Natural History of Congestive Heart Failure: The Framingham Study [DOI]
- 3 Obesity-Associated Hypertension [DOI]
- 4 Visceral Obesity [DOI]
- 5 Dysfunction of Endothelial Nitric Oxide Synthase and Atherosclerosis [DOI]
- 6 The Concept of Metabolic Syndrome: Contribution of Visceral Fat Accumulation and Its Molecular Mechanism [DOI]
- 7 Association of Body Fat Distribution and Cardiovascular Risk Factors in Children and Adolescents [DOI]
- 8 Epidemiological Transition and the Double Burden of Disease in Accra, Ghana [DOI]
- 9 The New BMI Criteria for Asians by the Regional Office for the Western Pacific Region of WHO are Suitable for Screening of Overweight to Prevent Metabolic Syndrome in Elder Japanese Workers [DOI]
- 10 Obesity-Related Hypertension: Epidemiology, Pathophysiology, and Clinical Management [DOI]
- 11 Endothelial function and nitric oxide: clinical relevance [DOI]
- 12 Dyslipidemia and the Risk of Incident Hypertension in Men [DOI]
- 13 Pathophysiology and Pathogenesis of Visceral Fat Obesity [DOI]
- 14 Obesity and hypertension: two epidemics or one? [DOI]
- 15 Visceral Fat in Hypertension [DOI]
- 16 Mechanisms linking obesity to hypertension [DOI]
- 17 Epidemic of hypertension in Ghana: a systematic review [DOI]
- 18 A community programme to reduce salt intake and blood pressure in Ghana [ISRCTN88789643] [DOI]
- 19 Renal Sinus Fat and Poor Blood Pressure Control in Middle-Aged and Elderly Individuals at Risk for Cardiovascular Events [DOI]
- 20 LIPITENSION : Interplay between dyslipidemia and hypertension [DOI]
- 21 G-Protein-Coupled Receptor Kinase 2 and Hypertension [DOI]
- 22 Physical activity ameliorates cardiovascular health in elderly subjects: the functional role of the β adrenergic system [DOI]
- 23 Coronary Heart Disease Risk Factors in the Elderly [DOI]
- 24 Recommendations for prevention, diagnosis and management of hypertension and cardiovascular risk factors in sub-Saharan Africa [DOI]
- 25 The relationship of waist circumference to blood pressure: the Olivetti heart study1 [DOI]
- 26 Visceral Fat Is a Major Contributor for Multiple Risk Factor Clustering in Japanese Men With Impaired Glucose Tolerance [DOI]
- 27 Blood pressure patterns in rural, semi-urban and urban children in the Ashanti region of Ghana, West Africa [DOI]
- 28 Stroke in Ashanti region of Ghana.
- 29 Pathophysiology and pathogenesis of visceral fat obesity [DOI]
- 30 Results of the Women's Health Study of Accra: Assessment of blood pressure in urban women [DOI]
- 31 Serum Lipid Profile of Newly Diagnosed Hypertensive Patients inNnewi, South‐East Nigeria [DOI]
- 32 Body Size and Blood Pressure [DOI]
- 33 Hypertensive Target Organ Damage in Ghanaian Civil Servants with Hypertension [DOI]
- 34 Interest in healthy living outweighs presumed cultural norms for obesity for Ghanaian women [DOI]
- 35 Measures of general and central obesity and risk of type 2 diabetes in a Ghanaian population [DOI]
- 36 Cardiovascular disease prevention in Ghana: feasibility of a faith-based organizational approach [DOI]
- 37 Prevalence and Aetiology of Heart Failure in Patients Seen at a Teaching Hospital in Ghana [DOI]
- 38 Prevalence and Risk Factors for Hypertension in Adansi South, Ghana [DOI]
- 39 Altered Relationship of Blood Pressure to Adiposity in Hypertension [DOI]
- 40 Obesity and Cardiovascular Risk Factors in a Pentecostal Population in Kumasi-Ghana [DOI]
- 41 Relationship Between Blood Pressure and Anthropometry in a Cohort of Brazilian Men: A Cross-Sectional Study [DOI]
- 42 Putative risk factors of pregnancy-induced hypertension among Ghanaian pregnant women
- 43 Comparative Analysis of Serum Lipid Profile between Normotensive and Hypertensive Pakistani Pregnant Women [DOI]
- 44 Lipid lowering: another method of reducing blood pressure? [DOI]
- 45 Factors associated with hypertension awareness, treatment and control in rural Chinese [DOI]
- 46 Obesity, Adiposity Indices, and Blood Pressure; Ethnicity Does Matter [DOI]
- 47 The Relationship Between Lifestyle Variables, Blood Pressure and Dietary Habits of Male Adult Miners in Ghana [DOI]
- 48 190: Biochemical Markers and Lipid Profiles in a Multiethnic Hypertensive Population from the United Arab Emirates [DOI]
- 49 The metabolic syndrome: useful concept or clinical tool? Report of a WHO Expert Consultation [DOI]
- 50 Renal Sinus Adiposity and Hypertension [DOI]
- 51 Criteria and Classification of Obesity in Japan and Asia-Oceania [DOI]
- 52 Epidemiology of cardiovascular disease in the 21st century: Updated updated numbers and updated facts
- 53 Causes Of Heart Failure As Seen In Kumasi Ghana [DOI]
- 54 Lipid disorders in hospital attendants in Kumasi, Ghana.
- 55 Cardiomegaly in Ghana: An Autopsy Study
- 56 Cardiovascular Risk Profile Of Patients Seen At A Cardiac Clinic In Kumasi, Ghana.
- 57 Dyslipidemia in outpatients at General Hospital in Kumasi, Ghana: cross-sectional study.
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Chudong Shan, Zhiyong Yuan, Zekang Qiu · 2022 International Joint Conference on Neural Networks (IJCNN) · 2022
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Christiana Aryee, William K. B. A. Owiredu, James Osei-Yeboah · International Journal of Hypertension · 2016
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