Patterns of Antibiotic Resistance in Niger Delta University Teaching Hospital, Okolobiri, Bayelsa State, Nigeria

Abstract

Aim: Identification of resistance pattern in some clinical isolates from Niger Delta University Teaching Hospital, Okolobiri, Nigeria. Study Design: Cross-sectional and descriptive study design were utilized in this study. Place and Duration of Study: Niger Delta University Teaching Hospital Okolobiriand Niger Delta University Molecular Laboratory CHS, Wilberforce Island, Amassoma, between February 2023 and April 2023. Methodology: This study was specifically carried out on clinical isolates with a population figure obtained from 6 different samples collected from Niger Delta University Teaching Hospital, okolobiri in Bayelsa state. From 500 different clinical samples, 100 clinical isolates were isolated and identified using Standard Bacteriological methods. Antibiotic susceptibility testing was carried out using Modified Kirby Bauer disc-diffusion method. Results: The findings showed that out of 100 isolates identified, Pseudomonas aeruginosa was most prevalent, 22(22%), 20(20%) were Klebsiella oxytoca, and 20(20%) were Escherichia coli. Antibiotics susceptibility pattern of the bacterial isolates revealed high resistance rates among the isolates, with significant resistance to multiple antibiotics. Conclusion: There was a high multi-drug-resistant Gram-negative bacteria, therefore justifying the extent of resistance observed.