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Research Article Open access CC BY 4.0

Study Progress of Coronary Artery Damage in Kawasaki Disease

Rong Lu, ChunYan Gao, Bing Zhang, Fuyong Jiao

Asian Journal of Pediatric Research · pp. 1–9 · Published 6 Oct 2023

10.9734/ajpr/2023/v13i4285

Abstract

Kawasaki Disease (KD) is a vasculitis of unknown etiology commonly seen in infants and children. Children with Kawasaki disease are at risk for serious cardiovascular sequelae, especially coronary artery abnormalities, which can lead to myocardial ischemia, myocardial infarction, and sudden death. Coronary artery lesions (CAL) caused by Kawasaki disease has become one of the common acquired heart diseases in children in some countries and regions. This article reviews the current research progress on the mechanism, risk factors and treatment of coronary artery damage in Kawasaki disease, aiming to improve the long-term prognosis of vascular health management in children with KD, in order to provide references for clinicians.

Kawasaki disease coronary artery damage risk factors mechanism heal

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