Evaluation of Ocular Anterior Chamber Depth and Body Mass Index in Normal Blacks in a Nigerian City

Abstract

Aim: To evaluate ocular anterior chamber depth (ACD) and body mass index (BMI) in a normal population in Port Harcourt City Local Government Area (LGA), with a view to determine formulae in estimating intraocular lens power for cataract surgeries and possible association with angle closure glaucoma and other ocular pathological conditions.            Methods: This is a multi-stage study with inclusion criteria of Visual Acuity > 6/18, age greater than 18 years with no history of past ocular surgeries or trauma. Data obtained through a structured proforma included age, sex, tribe, occupation and level of education. Body Mass Index (BMI) was measured using a standard height and weight automated scale (SECA 769,220). Comprehensive ocular examination done and Anterior Chamber Depth (ACD) measured using Amplitude (A) scan ultrasonography (SONOMED PACSCAN 300AP). Data was analyzed using SPSS (Version 17), and p value was set at ≤ 0.05. Results: Four hundred and sixty six (466) subjects participated in the study made up of two hundred and twelve (212) males (45.5%) and two hundred and fifty four (254) females (54.5%) with M: F ratio of 1:1.2. The age range was 18-92 years and mean age of the subjects studied 43.0±14.2 years. Findings revealed mean ACD and Body Mass Index to be 3.1±0.5 mm and 26.9±6.2 kg/m2 respectively. The mean ACD was greater in males than females. There was a statistically significant relationship between age and ACD. Obesity was found to be higher in females (n=97; 78.2%) compared to the males among those with BMI >30Kg/m2 and this was found to be statistically significant (p=0.0001). A larger proportion of subjects with normal BMI and overweight BMI 25-29.5 Kg/m2 were males. There was a statistically significant difference in the ACD values between genders among those overweight (BMI 25- 29.5 Kg/m2) and the obese (BMI >30 Kg/m2). Conclusion: There was a statistically significant difference in the ACD values between genders among those overweight.