Quorum sensing and interspecies interactions in Stenotrophomonas maltophilia
Microbiology Research Journal International · pp. 414–422 · Published 29 Jun 2013
10.9734/BMRJ/2013/4291Abstract
Stenotrophomonas maltophilia is a gram-negative bacterium that is widespread in the environment and that has become important in the last years as an emerging opportunistic pathogen. Quorum sensing (QS) is a bacterial cell–cell communication process that involves the production, detection, and response to extracellular signalling molecules called autoinducers. S. maltophilia has a diffusible signal factor (DSF) that controls cell–cell communication and many functions such as motility, extracellular protease production and microcolonies formation in artificial sputum medium. This DSF signalling mediates also interspecies interactions between S. maltophilia and Pseudomonas aeruginosa such as susceptibility to polymixin and its influence on biofilm formation. The traditional approach for the treatment of infectious diseases is to kill or inhibit the growth of bacteria using antibiotics. In response to the rise in antibiotic resistance, the development and use of QS inhibition based drugs to attenuate bacterial pathogenicity is now highly required in the microbiological and clinical fields.
Cited by 8
Neža Mrzdovnik, J. Babič, Dane Lužnik · Research in Veterinary Science · 2025
Dafne Guillén-Navarro, R. González-Vázquez, Gloria León-Ávila · Pathogens · 2023
S. Tripathi, Ram Chandra, D. Purchase · Environmental Pollution · 2021
A. Trifonova, T. Strateva · Infectious Diseases · 2018
R. I. Amoli, J. Nowroozi, A. Sabokbar · 2016
N. Mangwani, Supriya Kumari, Surajit Das · Biotechnology & Genetic Engineering Reviews · 2016
K. A. al-Anazi, A. M. al-Jasser · Frontiers in Oncology · 2014
NA Związki Przeciwbakteryjne, Olga Zając, A. Laudy · 2014
Related research
- Antibiofilm and Antibacterial Properties of Herbal Extracts as Alternatives to Current Treatment Approaches: A Narrative Review — shares topic coverage
- Anti-Quorum Sensing Activity of Tetracera scandens and Aleurites moluccana Leaf Extracts against Chromobacterium violaceum — shares topic coverage
- Quorum Sensing Inhibitors: The Novel Bacterial Infection Disrupting Agents — shares topic coverage
- Farnesol Sensitivity of Serum Induced Yeast to Hyphae Morphogenesis: A Study on Fifty Clinical Isolates of Candida albicans — shares topic coverage
- A Rapid Method to Screen for Multi Drug Resistance (MDR) Trait in Clinical Isolates of Acinetobacter baumannii-Acyl Homoserine Lactone (AHL) Screening in CRAB and CSAB Isolates — shares topic coverage
Article metrics
Real usage data collected on this platform.
0
Page views
0
PDF downloads
0
Outbound clicks
8
Citations
Views by country
Approximate, from request IP at view time — not citizenship or institution. Countries with fewer than 5 views are grouped as "Other".
No views recorded yet.
Traffic sources
Referring site, by host.
No traffic recorded yet.
Views and downloads exclude known bots/crawlers. Citations combines this platform's own DOI-resolved index with each external source's own reported total — see Cited by above for individually listed citing works. Last refreshed 0 seconds ago.