Bixa orellana Derived Phytochemicals against Entamoeba histolytica Causing Dysentery
Sonali Parida, Jogesh Kumar Nayak, Anindita Jena, Arsia Tabish, Archita Sahoo, Ananya Pani, Rukmini Mishra
Journal of Pharmaceutical Research International · pp. 97–100 · Published 3 Jun 2020
10.9734/jpri/2020/v32i830524Abstract
Phytochemicals from Bixa orellana plant extract are traditionally used to cure Dysentery. It is caused by Entamoeba histolytica. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that benzoin acid can effectively deactivate the alcohol dehydrogenase enzyme thereby interrupting the life cycle of the organism.
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