Capsicum Derived Phytochemicals against Shikimate Dehydrogenase of Haemophilus  influenza causing Bronchitis

Debesh Kumar Hota; Debadatta Nayak; Sitaram Swain; Dipankar Bhattacharyay

doi:10.9734/jpri/2020/v32i630507

Research Article Open access CC BY 4.0

Capsicum Derived Phytochemicals against Shikimate Dehydrogenase of Haemophilus influenza causing Bronchitis

Debesh Kumar Hota, Debadatta Nayak, Sitaram Swain, Dipankar Bhattacharyay

Journal of Pharmaceutical Research International · pp. 128–131 · Published 15 May 2020

10.9734/jpri/2020/v32i630507

Abstract

Phytochemicals from Capsicum plant extract are traditionally used to cure Bronchitis. It is caused by Haemophilus influenzae. Molecular docking method applied using “Biovia Discovery Studio”. “High positive values of -CDOCKER energy and -CDOCKER interaction energy” suggested that Apigenin can effectively deactivate the Shikimate dehydrogenase enzyme thereby interrupting the life cycle of the organism.

Phytochemical capsicum Haemophilus influenza

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Debesh Kumar Hota, Debadatta Nayak, Sitaram Swain, Dipankar Bhattacharyay (2020). Capsicum Derived Phytochemicals against Shikimate Dehydrogenase of Haemophilus influenza causing Bronchitis. Journal of Pharmaceutical Research International , 128–131. https://doi.org/10.9734/jpri/2020/v32i630507

Affiliations

Debesh Kumar Hota — Centurion University of Technology and Management, Odisha, India.
Debadatta Nayak — Centurion University of Technology and Management, Odisha, India.
Sitaram Swain — Centurion University of Technology and Management, Odisha, India.
Dipankar Bhattacharyay — Centurion University of Technology and Management, Odisha, India. and Go to Market Laboratory, Gram Tarang, Odisha, India.

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