Characterization of Chemical Composition of Bryophyllum pinnatum Leaf Ethyl Acetate Fraction
E. S. Asiwe, C. U. Igwe, V. A. Onwuliri, K. M. E. Iheanacho, J. N. Iheanacho
Asian Journal of Advanced Research and Reports · pp. 15–24 · Published 13 Jul 2021
10.9734/ajarr/2021/v15i430387Abstract
Aims: To characterize the chemical composition of Bryophyllum pinnatum leaf ethyl acetate fraction. Methodology: Quantitative phytochemical composition was assessed using gas chromatography fitted with flame ionization detector (GC-FID), while chemical characterization was via gas chromatography-mass spectrophotometry (GC-MS) analysis. The mass spectra peaks were matched with those found in the National Institute of Standard and Technology (NIST) spectral database. Results: Results revealed a rich presence of proanthocyanin, rutin, quinine, flavan-3-ol, anthocyanin, lunamarin, sapogenin, phenol, flavonones, steroids, epicatechin, kaempferol, phytate, oxalate, resveratol, catechin, flavones, tannin, ribalinidine, naringin, and spartein in varying proportion in B. pinnatum leaves ethylacetate fractions. GC-MS analysis of the fractions revealed the presence of at least 50 constituents. The major constituents were Hexadecanoic acid, methyl ester (24.88%), 10,13-Octadecadienoic acid, methyl ester (29.69%), Tetracosanoic acid, methyl ester (7.84%), Methyl stearate (6.97%), cis-Methyl 11-eicosenoate (6.26%), Methyl 18-methylnonadecanoate (4.99%), Docosanoic acid, methyl ester (3.71%) and 4,7-Methano-1H-indene, octahydro- (2.43%). Conclusion: This rich array of chemical compounds presents B. pinnatum leaves as an important source of potential lead compounds with biological and pharmacological benefits and hence a potential candidate for drug discovery.
References (29)
- 1 Antioxidant properties of phenolic compounds [DOI]
- 2 Health effects of quercetin: From antioxidant to nutraceutical [DOI]
- 3 Antioxidant Activity in Fruits and Leaves of Blackberry, Raspberry, and Strawberry Varies with Cultivar and Developmental Stage [DOI]
- 4 Health benefits of herbs and spices: the past, the present, the future [DOI]
- 5 The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease [DOI]
- 6 Dietary Flavonoids and the Risk of Lung Cancer and Other Malignant Neoplasms [DOI]
- 7 Preparation of fatty acid methyl esters for gas-liquid chromatography [DOI]
- 8 The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways [DOI]
- 9 Protective Effect of Fruits and Vegetables on Development of Stroke in Men [DOI]
- 10 Natural antioxidants in grapes and wines [DOI]
- 11 Quercetin reduces obesity-associated ATM infiltration and inflammation in mice: a mechanism including AMPKα1/SIRT1 [DOI]
- 12 A Review of the Cardiovascular Benefits and Antioxidant Properties of Allicin [DOI]
- 13 Antibacterial and antifungal efficacy of fatty acid methyl esters from the leaves of Sesuvium portulacastrum L.
- 14 Seasonal consumption of salad vegetables and fresh fruit in relation to the development of cardiovascular disease and cancer [DOI]
- 15 Isolation and characterization of methyl esters and derivatives from Euphorbia kansui (Euphorbiaceae) and their inhibitory effects on the human SGC-7901 cells.
- 16 Bryophyllum pinnatum (Lam.) Kurz.: Phytochemical and Pharmacological Profile : A Review
- 17 Protective effect of Kalanchoe pinnata pers. (Crassulaceae) on gentamicin-induced nephrotoxicity in rats [DOI]
- 18 Antiherpes virus activity of extracts from the medicinal plant Geranium sanguineum L. [DOI]
- 19 Phenolic Acids Are in Vivo Atheroprotective Compounds Appearing in the Serum of Rats after Blueberry Consumption [DOI]
- 20 Plants in the Development of Modern Medicine [DOI]
- 21 Grape Seed and Grape Skin Extracts Elicit a Greater Antiplatelet Effect When Used in Combination than When Used Individually in Dogs and Humans [DOI]
- 22 Intravenous tocolysis with Bryophyllum pinnatum is better tolerated than beta-agonist application [DOI]
- 23 Butein induces cell apoptosis and inhibition of cyclooxygenase-2 expression in A549 lung cancer cells [DOI]
- 24 Stilbenoids from Gnetum macrostachyum Attenuate Human Platelet Aggregation and Adhesion [DOI]
- 25 Modulation of Aromatase Activity by Diet Polyphenolic Compounds [DOI]
- 26 Role of ROS and COX-2/iNOS inhibition in cancer chemoprevention: a review [DOI]
- 27 ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF BRYOPHYLLUM CALYCINUM SALISB LEAF
- 28 Renal and Hepato-Protective Effects of Irvingia gabonensis Juice on Sodium Fluoride-Induced Toxicity in Wistar Rats [DOI]
- 29 Proximate and elemental composition of Bryophyllum pinnatum (Lim)
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