Clinicoradiological Correlation of Crouzon Syndrome – A Case Report

Abstract

Crouzon's syndrome is a rare autosomally dominant genetic disorder with complete penetrance and variable expressivity. In 1912 a French neurosurgeon first described this disorder. There is a mutation in the fibroblast growth factor receptor 2 (FGFR2) gene which causes this syndrome. Crouzon's syndrome is characterised by premature closure of sutures in the skull predominantly involving coronal and sagittal suture resulting in interference in the growth of the brain.