Correlation between Serum Uric Acid and Blood Pressure in Plateau Central

Abstract

Aim: To determine the Correlation between Serum uric acid (SUA) and Blood Pressure in Plateau Central. Background: Serum uric acid, an end product of purine metabolism, has been shown to be associated with an increased risk of hypertension cardiovascular4 and chronic kidney disease in previous epidemiological studies. Elevated SUA has been shown to predict the development of high blood pressure and may contribute to increasing BP by several mechanisms. Clinical trials in young patients have supported this mechanism but do not yet agree with pharmacologic reduction of SUA as first-line therapy for hypertension. Materials and Methods: 200 (males and females) subject of Panyam district of Mangu L. G. C. in Plateau central formed the study population with aged 40 - 90 years. The intervention groups were 120 and control group was 80. Five ml of blood was aliquoted for assay uric acid for each subject using the enzymatic uricase method. Results: The data obtained were coded into Stata Software for analysis. The data was presented as mean ± S.D. comparison was done by student’s t-test for continuous variables. A BMI of >30 kg/m2 was found in 31 individuals giving a prevalence 15.5% with SUA prevalence of 41% with 32% being the prevalence of hypertension. Conclusion: The rural farmers were found to have high SUA and positively correlated to hypertension. With the high level of SUA and high BP, advocacy should be made on regular BP checks and possible provision of personal portable BP machine for self-monitoring.