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Research Article Open access CC BY 4.0

Macrophagic Activation Syndrome Revealing Hodgkin Lymphoma: Case Report

Nadia Mebrouk, Rachid Abilkassem, Anass Ayad, Aomar Agadr

Asian Journal of Pediatric Research · pp. 7–10 · Published 17 Aug 2022

10.9734/ajpr/2022/v9i330266

Abstract

Macrophage Activation Syndrome (MAS), or Haemophagocytosis Syndrome, is a clinical-biological entity characterized by the proliferation and non-specific activation of macrophages of the reticulo-histiocytic system, with phagocytosis of the blood elements formed. This syndrome can be primary in children or secondary to various conditions at any age. Its association with Hodgkin's lymphoma is exceptional. We report here a case of MAS that revealed Hodgkin's lymphoma in a 5-year-old child. And we underline the interest of an urgent diagnosis and a fast care because risk of evolution towards a fatal multivisceral failure.

Macrophage activation syndrome MAS hemophagocytosis syndrome Hodgkin's lymphoma

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